Molecular architecture with functionalized β-peptide helices

被引：68
作者：
Brückner, AM
Chakraborty, P
Gellman, SH
Diederichsen, U
机构：
[1] Univ Gottingen, Inst Organ Chem, D-37077 Gottingen, Germany
[2] Univ Wisconsin, Dept Chem, Madison, WI 53706 USA
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2003年 / 42卷 / 36期
关键词：
base pairing; beta-peptides; helical structures; secondary structure; self-assembly;
D O I：
10.1002/anie.200351871
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Specific recognition of β-peptide helices can be achieved by the incorporation of nucleo-β-amino acids in every third position of β-peptide oligomers. Pairing complexes (see picture) are formed with extraordinary high stabilities in aqueous buffer. A major contribution comes from the high preorganization of the nucleobases by the 14-helix backbone.
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收藏
页码：4395 / 4399
页数：5
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