Single-Molecule Detection of Proteins Using Aptamer-Functionalized Molecular Electronic Devices

被引：98
作者：
Liu, Song [1 ]
Zhang, Xinyue [2 ]
Luo, Wangxi [2 ]
Wang, Zhenxing [1 ]
Guo, Xuefeng [1 ]
Steigerwald, Michael L. [3 ,4 ]
Fang, Xiaohong [2 ]
机构：
[1] Peking Univ, Coll Chem & Mol Engn, State Key Lab Struct Chem Unstable & Stable Speci, Beijing Natl Lab Mol Sci, Beijing 100871, Peoples R China
[2] Chinese Acad Sci, Inst Chem, Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China
[3] Dept Chem, New York, NY USA
[4] Columbia Univ, Ctr Elect Mol Nanostruct, New York, NY USA
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2011年 / 50卷 / 11期
关键词：
aptamers; biosensors; molecular devices; nanotubes; PROSTATE-SPECIFIC ANTIGEN; LABEL-FREE; ELECTRICAL DETECTION; CARBON NANOTUBES; REAL-TIME; DNA; THROMBIN; FABRICATION; ANTIBODY; BIOLOGY;
D O I：
10.1002/anie.201006469
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Filling in the gap: Label-free, real-time electrical detection of proteins is achieved with high selectivity and real single-molecule sensitivity by using aptamer-functionalized molecular electronic devices with single-walled carbon nanotubes as point contacts. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码：2496 / 2502
页数：7
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