Monte Carlo Simulations of Prompt-Gamma Emission During Carbon Ion Irradiation

被引：34

作者：

Le Foulher, F. ^{[1
,2
]}

Bajard, M. ^{[1
,2
]}

Chevallier, M. ^{[1
,2
]}

Dauvergne, D. ^{[1
,2
]}

Freud, N. ^{[3
]}

Henriquet, P. ^{[1
,2
]}

Karkar, S. ^{[4
]}

Letang, J. M. ^{[3
]}

Lestand, L. ^{[5
]}

Plescak, R. ^{[6
]}

Ray, C. ^{[1
,2
]}

Schardt, D. ^{[6
]}

Testa, E. ^{[1
,2
]}

Testa, M. ^{[1
,2
]}

机构：

[1] Univ Lyon, F-69003 Lyon, France

[2] Inst Phys Nucl, CNRS, IN2P3, UMR 5822, F-69622 Villeurbanne, France

[3] INSA Lyon, Lab Controles Non Destructifs Rayonnements Ionisa, F-69621 Villeurbanne, France

[4] Aix Marseille Univ, CPPM, CNRS, IN2P3, Marseille, France

[5] Univ Blaise Pascal, LPC Clermont, CNRS, IN2P3, F-63177 Clermont Ferrand, France

[6] Gesell Schwerionenforsch GSI, D-64291 Darmstadt, Germany

来源：

IEEE TRANSACTIONS ON NUCLEAR SCIENCE | 2010年 / 57卷 / 05期

关键词：

Dose profile; Geant4; simulation; hadrontherapy; prompt-gamma ray; THERAPY; VERIFICATION;

D O I：

10.1109/TNS.2010.2048042

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

Monte Carlo simulations based on the Geant4 toolkit (version 9.1) were performed to study the emission of secondary prompt-gamma rays produced by nuclear reactions during carbon ion-beam therapy. These simulations were performed along with an experimental program and instrumentation developments which aim at designing a prompt-gamma ray device for real-time control of hadrontherapy. The objective of the present study is twofold: firstly, to present the features of the prompt-gamma radiation in the case of carbon ion irradiation; secondly, to simulate the experimental setup and to compare measured and simulated counting rates corresponding to four different experiments. For each experiment, we found that simulations overestimate prompt-gamma ray detection yields by a factor of 12. Uncertainties in fragmentation cross sections and binary cascade model cannot explain such discrepancies. The so-called "photon evaporation" model is therefore questionable and its modification is currently in progress.

引用

页码：2768 / 2772

页数：5

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