Studies of self-assembly of collagen type I molecules without telopeptides

被引：0

作者：

Nikolaeva, TI ^{[1
]}

Pisachenko, AI ^{[1
]}

Selezneva, II ^{[1
]}

Rochev, YA ^{[1
]}

Gavrilyuk, BK ^{[1
]}

机构：

[1] Russian Acad Sci, Inst Theoret & Expt Biophys, Pushchino 142290, Moscow Region, Russia

来源：

BIOFIZIKA | 2000年 / 45卷 / 06期

关键词：

self-assembly; collagen; telopeptide; temperature; kinetics; enthalpy;

D O I：

暂无

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

The effect of temperature on the kinetics of formation of fibrils from rat tail collagen molecules devoid of telopeptides was studied. It was shown that the rats of fibril formation at 30 and 35 degreesC increases five- and eightfold, respectively, as compared with that at 25 degreesC. It was found that enthalpy of fibril denaturation at 30 degreesC is maximal for the collagen both with intact telopeptides and devoid of telopeptides. It was found that essential for the fibrilogenesis of type I collagen devoid of telopeptides are temperatures of 30 and 35 degreesC.

引用

页码：1146 / 1149

页数：4

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