The management of moderate-to-severe chronic plaque psoriasis

被引：2
作者：
Tonini, Annalisa [1 ]
Panduri, Salvatore [1 ]
D'Erme, Angelo M. [1 ,2 ]
Papadia, Francesca [1 ]
Romaneli, Marco [1 ]
Krueger, James G. [3 ]
Chiricozzi, Andrea [1 ]
机构：
[1] Univ Pisa, Dept Dermatol, Via Roma 67, Pisa, Italy
[2] Livorno Hosp, Unit Dermatol, Livorno, Italy
[3] Rockefeller Univ, Lab Invest Dermatol, 1230 York Ave, New York, NY 10021 USA
来源：
GIORNALE ITALIANO DI DERMATOLOGIA E VENEREOLOGIA | 2017年 / 152卷 / 05期
关键词：
Psoriasis; Apremilast; Therapeutics; PLACEBO-CONTROLLED TRIAL; INTERLEUKIN-12/23; MONOCLONAL-ANTIBODY; PHASE-III TRIALS; QUALITY-OF-LIFE; DOUBLE-BLIND; SYSTEMIC TREATMENTS; VS; METHOTREXATE; RANDOMIZED-TRIAL; DRUG SURVIVAL; SAFETY;
D O I：
10.23736/S0392-0488.17.05681-4
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Recent approval and marketization of novel treatments have widened the range of therapeutic opportunities for moderate-to-severe psoriasis. In the next years, this panorama will be further enlarged as many other agents, both oral small molecules and biologics, have passed phase III and are expected to be approved, and subsequently marketed, shortly. In spite of this array of therapeutic possibilities, there is still an unmet need for an appropriate treatment in a large number of cases. This review was aimed to describe general principles regarding the therapeutic approach to moderate-severe plaque psoriasis, providing an updated overview of the therapeutic armamentarium that is specifically available in Italy, drug prescriptibility, and some peculiar limitations for reimbursement defined by our National Health Care System.
引用
收藏
页码：447 / 457
页数：11
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