Neuropathological studies on dementia with Lewy bodies

被引：0

作者：

Kosaka, K ^{[1
]}

Iseki, E ^{[1
]}

机构：

[1] Yokohama City Univ, Sch Med, Dept Psychiat, Yokohama, Kanagawa 2360004, Japan

来源：

CONTEMPORARY NEUROPSYCHIATRY | 2001年

关键词：

Lewy body; diffuse Lewy body disease; dementia with Lewy bodies; alpha-synuclein; immunohistochemistry;

D O I：

暂无

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We review here some of our recent neuropathological studies of dementia with Lewy bodies (DLB). Using immunohistochemistry with anti-alpha -synuclein and other antibodies, we point out (1) the possibility of dying-back degeneration in hippocampal pathology, (2) more frequent coexistence of Lewy bodies and neurofibrillary tangles in the same neurons in the limbic areas than expected, and (3) the degeneration process of Lewy bodies, that the Lewy body degenerates slowly and appear extracellularly (ghost Lewy body) followed by microglias and astrocytes.

引用

页码：187 / 189

页数：3

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