Differential Changes in Myocardial Performance Index and Its Time Intervals in Donors and Recipients of Twin-to-Twin Transfusion Syndrome before and after Laser Therapy

被引：9
作者：
Ortiz, Javier U. [1 ,2 ,3 ,4 ]
Torres, Ximena [1 ,2 ,3 ]
Eixarch, Elisenda [1 ,2 ,3 ]
Bennasar, Mar [1 ,2 ,3 ]
Cruz-Lemini, Monica [1 ,2 ,3 ,5 ]
Gomez, Olga [1 ,2 ,3 ]
Lobmaier, Silvia M. [1 ,2 ,3 ,4 ]
Martinez, Josep M. [1 ,2 ,3 ]
Gratacos, Eduard [1 ,2 ,3 ]
Crispi, Fatima [1 ,2 ,3 ]
机构：
[1] Univ Barcelona, Hosp Clin, BCNatal Barcelona Ctr Maternal Fetal & Neonatal M, Barcelona, Spain
[2] Univ Barcelona, IDIBAPS, Hosp Sant Joan Deu, Barcelona, Spain
[3] Ctr Biomed Res Rare Dis CIBER ER, Barcelona, Spain
[4] Tech Univ Munich, Frauenklin & Poliklin, Munich, Germany
[5] UNAM, Inst Neurobiol, Unidad Invest Neurodesarrollo, Fetal Med Mexico,Fetal Med & Surg Res Unit, Campus Juriquilla, Queretaro, Mexico
来源：
FETAL DIAGNOSIS AND THERAPY | 2018年 / 44卷 / 04期
关键词：
Twin-to-twin transfusion syndrome; Myocardial performance index; Laser therapy; Donor twin; Recipient twin; CONVENTIONAL DOPPLER; AORTIC ISTHMUS; DUCTUS VENOSUS; CARDIOMYOPATHY; DEFORMATION; PARAMETERS; FETUSES; IMPACT;
D O I：
10.1159/000485380
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
Objective: To evaluate left myocardial performance index (MPI) and time intervals in fetuses with twin-to-twin transfusion syndrome (TTTS) before and after laser surgery. Methods: Fifty-one fetal pairs with TTTS and 47 uncomplicated monochorionic twin pairs were included. Left ventricular isovolumetric contraction time (ICT), ejection time (ET), and isovolumetric relaxation time (IRT) were measured using conventional Doppler. Results: Recipients showed prolonged ICT (46 +/- 12 vs. 31 +/- 8 vs. 30 +/- 5 ms; p < 0.001) and IRT (51 +/- 9 vs. 43 +/- 8 vs. 43 +/- 5 ms; p < 0.001) and higher MPI (0.57 +/- 0.12 vs. 0.47 +/- 0.09 vs. 0.44 +/- 0.05; p < 0.001) than donors and controls. Donors showed shorter ET than recipients and controls (157 +/- 12 vs. 169 +/- 10 vs. 168 +/- 10 ms; p < 0.001) and higher MPI than controls (0.47 +/- 0.09 vs. 0.44 +/- 0.05; p = 0.006). Preoperative MPI changes were observed in all TTTS stages. Time intervals partially improved after surgery. Conclusion: Donor and recipient twins had higher MPI due to different changes in the time intervals, possibly reflecting the state of hypovolemia in the donor and hypervolemia and pressure overload in the recipient.
引用
收藏
页码：305 / 310
页数：6
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