Contactless microparticle control via ultrahigh frequency needle type single beam acoustic tweezers

被引:33
作者
Fei, Chunlong [1 ,2 ,3 ]
Li, Ying [2 ,3 ]
Zhu, Benpeng [4 ]
Chiu, Chi Tat [2 ,3 ]
Chen, Zeyu [2 ,3 ]
Li, Di [1 ]
Yang, Yintang [1 ]
Shung, K. Kirk [2 ,3 ]
Zhou, Qifa [1 ,2 ,3 ]
机构
[1] Xidian Univ, Sch Microelect, Xian 710071, Peoples R China
[2] Univ Southern Calif, NIH Resource Ctr Med Ultrason Transducer Technol, Los Angeles, CA 90089 USA
[3] Univ Southern Calif, Dept Biomed Engn, Los Angeles, CA 90089 USA
[4] Huazhong Univ Sci & Technol, Sch Opt & Elect Informat, Wuhan 430074, Peoples R China
基金
中国国家自然科学基金; 美国国家卫生研究院;
关键词
ULTRASONIC TRANSDUCERS; MANIPULATION; SEPARATION; FORCE;
D O I
10.1063/1.4966285
中图分类号
O59 [应用物理学];
学科分类号
摘要
This paper reports on contactless microparticle manipulation including single-particle controlled trapping, transportation, and patterning via single beam acoustic radiation forces. As the core component of single beam acoustic tweezers, a needle type ultrasonic transducer was designed and fabricated with center frequency higher than 300 MHz and -6 dB fractional bandwidth as large as 64%. The transducer was built for an f-number close to 1.0, and the desired focal depth was achieved by press-focusing technology. Its lateral resolution was measured to be better than 6.7 mu m by scanning a 4 mu m tungsten wire target. Tightly focused acoustic beam produced by the transducer was shown to be capable of manipulating individual microspheres as small as 3 mu m. "USC" patterning with 15 mu m microspheres was demonstrated without affecting nearby microspheres. These promising results may expand the applications in biomedical and biophysical research of single beam acoustic tweezers. Published by AIP Publishing.
引用
收藏
页数:4
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