Effectiveness and Safe Use of Modified FOLFOX-6 for Metastatic Gastric Cancer with Signet Ring Cell Components Complicated by Disseminated Intravascular Coagulation and Diffuse Bone Marrow Carcinomatosis

被引：7

作者：

Ferrand, Francois-Regis ^{[1
]}

Gontier, Eric ^{[2
]}

Guymar, Sophie ^{[3
]}

Fagot, Thierry ^{[4
]}

Ceccaldi, Bernard ^{[1
]}

Malfuson, Jean-Valere ^{[4
]}

de Revel, Thierry ^{[4
]}

机构：

[1] HIA Val de Grace, Serv Oncol, F-75005 Paris, France

[2] HIA Val de Grace, Nucl Med Serv, F-75005 Paris, France

[3] HIA Begin, Serv Anatomopathol, St Mande, France

[4] HIA Percy, Serv Hematol, Clamart, France

来源：

ONKOLOGIE | 2012年 / 35卷 / 03期

关键词：

Gastric cancer; Disseminated intravascular coagulation; Chemotherapy; CLINICOPATHOLOGICAL FEATURES; 5-FLUOROURACIL; OXALIPLATIN; LEUCOVORIN; PLUS;

D O I：

10.1159/000336971

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

We report the case of a 62-year-old woman with a metastatic gastric cancer complicated by diffuse bone marrow carcinomatosis, disseminated intravascular coagulation (DIC) and microangiopathic hemolytic anemia (MHA) treated by modified FOLFOX-6 as front-line chemotherapy regimen. This chemotherapy showed clinical, morphological and biological efficiency and safety in this rare and severe hematological complication at initial diagnosis. Furthermore, this is the first case of diffuse bone carcinomatosis from a gastric cancer to be monitored by positron emission tomography integrated computed tomography (PET-CT) scan using 18-fluorodeoxyglucose (18-FDG).

引用

页码：118 / 120

页数：3

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