Discovery of a Potent and Selective Coactivator Associated Arginine Methyltransferase 1 (CARM1) Inhibitor by Virtual Screening (vol 59, pg 6838, 2016)

被引:1
作者
de Freitas, Renato Ferreira
Eram, Mohammad S.
Smil, David
Szewczyk, Magdalena M.
Kennedy, Steven
Brown, Peter J.
Santhakumar, Vijayaratnam
Barsyte-Lovejoy, Dalia
Arrowsmith, Cheryl H.
Vedadi, Masoud
Schapira, Matthieu
机构
关键词
D O I
10.1021/acs.jmedchem.6b01095
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
引用
收藏
页码:7698 / 7698
页数:1
相关论文
共 50 条
[41]   From protein to candidate: Discovery of EPZ-5676, a potent and selective inhibitor of the histone methyltransferase DOT1L [J].
Chesworth, Richard ;
Olhava, Edward J. ;
Kuntz, Kevin W. ;
Basavapathruni, Aravind ;
Majer, Christina R. A. ;
Sneeringer, Chris J. ;
Allain, Christina J. ;
Raimondi, Alejandra ;
Klaus, Christine R. ;
Scott, Margaret Porter ;
Therkelsen, Carly A. ;
Daigle, Scott R. ;
Pollock, Roy M. ;
Richon, Victoria M. ;
Copeland, Robert A. ;
Boriack-Sjodin, Ann ;
Jin, Lei ;
Waters, Nigel J. ;
Arnold, Lee ;
Patane, Michael ;
Pearson, Paul ;
Sacks, Joelle ;
Moyer, Mikel P. .
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2013, 246
[42]   Discovery of indoles as potent and selective inhibitors of the deacetylase SIRT1 (vol 48, pg 8049, 2005) [J].
Napper, Andrew D. ;
Hixon, Jeffrey ;
McDonagh, Thomas ;
Keavey, Kenneth ;
Pons, Jean-Francois ;
Barker, Jonathan ;
Yau, Wei Tsung ;
Amouzegh, Patricia ;
Flegg, Adam ;
Hamelin, Estelle ;
Thomas, Russell J. ;
Kates, Michael ;
Jones, Stephen ;
Navia, Manuel A. ;
Saunders, Jeffrey O. ;
DiStefano, Peter S. ;
Curtis, Rory .
JOURNAL OF MEDICINAL CHEMISTRY, 2007, 50 (05) :1086-1086
[43]   Discovery of a Potent and Selective Sphingosine Kinase 1 Inhibitor through the Molecular Combination of Chemotype-Distinct Screening Hits [J].
Schnute, Mark E. ;
McReynolds, Matthew D. ;
Carroll, Jeffrey ;
Chrencik, Fill ;
Highkin, Maureen K. ;
Iyanar, Kaliapan ;
Jerome, Gina ;
Rains, John W. ;
Saabye, Matthew ;
Scholten, Jeffrey A. ;
Yates, Matthew ;
Nagiec, Marek M. .
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 60 (06) :2562-2572
[44]   Discovery of Novel 3-Quinoline Carboxamides as Potent, Selective, and Orally Bioavailable Inhibitors of Ataxia Telangiectasia Mutated (ATM) Kinase (vol 59, pg 6281, 2016) [J].
Degorce, Sebastien L. ;
Barlaam, Bernard ;
Cadogan, Elaine ;
Dishington, Allan ;
Ducray, Richard ;
Glossop, Steven C. ;
Hassall, Lorraine A. ;
Lach, Franck ;
Lau, Alan ;
McGuire, Thomas M. ;
Nowak, Thorsten ;
Ouvry, Gilles ;
Pike, Kurt G. ;
Thomason, Andrew G. .
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 61 (14) :6398-6398
[45]   Discovery of a Potent and Selective Covalent Inhibitor and Activity-Based Probe for the Deubiquitylating Enzyme UCHL1, with Antifibrotic Activity (vol 142, pg 12020, 2020) [J].
Panyain, Nattawadee ;
Godinat, Aurelien ;
Lanyon-Hogg, Thomas ;
Lachiondo-Ortega, Sofia ;
Will, Edward J. ;
Soudy, Christelle ;
Mondal, Milon ;
Mason, Katie ;
Elkhalifa, Sarah ;
Smith, Lisa M. ;
Harrigan, Jeanine A. ;
Tate, Edward W. .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2020, 142 (35) :15199-15199
[46]   Successful shape-based virtual screening:: the discovery of a potent inhibitor of the type I TGFβ receptor kinase (TβRI) (vol 13, pg 4355, 2003) [J].
Singh, J ;
Chuaqui, CE ;
Boriack-Sjodin, PA ;
Lee, WC ;
Pontz, T ;
Corbley, MJ ;
Cheung, HK ;
Arduini, RM ;
Mead, JN ;
Newman, MN ;
Papadatos, JL ;
Bowes, S ;
Josiah, S ;
Ling, LE .
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2004, 14 (11) :2991-2991
[47]   Discovery of Entrectinib: A New 3-Aminoindazole as a Potent Anaplastic Lymphoma Kinase (ALK), c-ros Oncogene 1 Kinase (ROS1), and Pan-Tropomyosin Receptor Kinases (Pan-TRKs) inhibitor (vol 59, pg 3392, 2016) [J].
Menichincheri, Maria ;
Ardini, Elena ;
Magnaghi, Paola ;
Avanzi, Nilla ;
Banfi, Patrizia ;
Bossi, Roberto ;
Buffa, Laura ;
Canevari, Giulia ;
Ceriani, Lucio ;
Colombo, Maristella ;
Corti, Luca ;
Donati, Daniele ;
Fasolini, Marina ;
Felder, Eduard ;
Fiorelli, Claudio ;
Fiorentini, Francesco ;
Galvani, Arturo ;
Isacchi, Antonella ;
Borgia, Andrea Lombardi ;
Marchionni, Chiara ;
Nesi, Marcella ;
Orrenius, Christian ;
Panzeri, Achille ;
Pesenti, Enrico ;
Rusconi, Luisa ;
Saccardo, Maria Beatrice ;
Vanotti, Ermes ;
Perrone, Ettore ;
Orsini, Paolo .
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 62 (17) :8364-8364
[48]   Design of Potent and Druglike Nonphenolic Inhibitors for Catechol O-Methyltransferase Derived from a Fragment Screening Approach Targeting the S-Adenosyl-L-methionine Pocket (vol 59, pg 10163, 2016) [J].
Lerner, Christian ;
Jakob-Roetne, Roland ;
Buettelmann, Bernd ;
Ehler, Andreas ;
Rudolph, Markus G. ;
Sarmiento, Rosa Maria Rodriguez .
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 60 (09) :4099-4099
[49]   Discovery of a potent and highly selective transforming growth factor β receptor-associated kinase 1 (TAK1) inhibitor by structure based drug design (SBDD) [J].
Muraoka, Terushige ;
Ide, Mitsuaki ;
Morikami, Kenji ;
Irie, Machiko ;
Nakamura, Mitsuaki ;
Miura, Takaaki ;
Kamikawa, Takayuki ;
Nishihara, Masamichi ;
Kashiwagi, Hirotaka .
BIOORGANIC & MEDICINAL CHEMISTRY, 2016, 24 (18) :4206-4217
[50]   Discovery of Potent Selective HDAC6 Inhibitors with 5-Phenyl-1H-indole Fragment: Virtual Screening, Rational Design, and Biological Evaluation [J].
Li, Xuedong ;
Wang, Chengzhao ;
Chai, Xu ;
Liu, Xingang ;
Qiao, Kening ;
Fu, Yan ;
Jin, Yanzhao ;
Jia, Qingzhong ;
Zhu, Feng ;
Zhang, Yang .
JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2024, 64 (15) :6147-6161