Asymmetric hydrogenation of alkenes lacking coordinating groups

被引：169

作者：

Woodmansee, David H. ^{[1
]}

Pfaltz, Andreas ^{[1
]}

机构：

[1] Univ Basel, Dept Chem, CH-4056 Basel, Switzerland

来源：

CHEMICAL COMMUNICATIONS | 2011年 / 47卷 / 28期

关键词：

CATALYZED ENANTIOSELECTIVE HYDROGENATION; TRISUBSTITUTED OLEFINS; IRIDIUM CATALYSTS; LIGANDS; COMPLEXES; ROUTE;

D O I：

10.1039/c1cc11430a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Asymmetric hydrogenation of olefins is one of the most important reactions for the synthesis of optically active compounds, especially in industry. Chiral iridium catalysts based on P,N ligands have strongly expanded their application range. In contrast to rhodium and ruthenium diphosphine complexes they do not require the presence of a coordinating group near the C=C bond and, therefore, allow highly enantioselective hydrogenations of largely unfunctionalized alkenes.

引用

页码：7912 / 7916

页数：5

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