Switch hitter: Bcl11b in T cells and ILC2s

被引：1

作者：

Harly, Christelle ^{[1
,2
]}

Bhandoola, Avinash ^{[3
]}

机构：

[1] Univ Nantes, Univ Angers, CNRS, INSERM,CRCINA, Nantes, France

[2] LabEx IGO Immunotherapy, Graft, Oncol, Nantes, France

[3] NCI, Lab Genome Integr, Ctr Canc Res, NIH, Bethesda, MD 20892 USA

来源：

JOURNAL OF EXPERIMENTAL MEDICINE | 2020年 / 217卷 / 01期

关键词：

D O I：

10.1084/jem.20191739

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

In this issue of JEM, Hosokawa et al. (https://doi.org/10.1084/jem.20190972) establish that transcription factor Bcl11b regulates almost completely distinct sets of genes in T cell precursors and ILC2s. To understand how this occurs, they identify multiple levels of functional regulation for Bcl11b that are used differently by T cell precursors and ILC2s.

引用

页数：2

共 50 条

[31] Basophils balance ILC2s [J].

Bird, Lucy .

NATURE REVIEWS IMMUNOLOGY, 2020, 20 (10) :592-+

[32] ILC2s skew the fat [J].

Yvonne Bordon .

Nature Reviews Immunology, 2015, 15 (2) :67-67

[33] Heterogeneity of ILC2s in the Lungs [J].

Asaoka, Masato ;

Kabata, Hiroki ;

Fukunaga, Koichi .

FRONTIERS IN IMMUNOLOGY, 2022, 13

[34] Basophils balance ILC2s [J].

Lucy Bird .

Nature Reviews Immunology, 2020, 20 :592-593

[35] Identification of BCL11B as a regulator of adipogenesis [J].

Inoue, Jun ;

Ihara, Yusuke ;

Tsukamoto, Daisuke ;

Yasumoto, Keisuke ;

Hashidume, Tsutomu ;

Kamimura, Kenya ;

Nakai, Yuji ;

Hirano, Shigeki ;

Shimizu, Makoto ;

Kominami, Ryo ;

Sato, Ryuichiro .

SCIENTIFIC REPORTS, 2016, 6

[36] Identification of BCL11B as a regulator of adipogenesis [J].

Jun Inoue ;

Yusuke Ihara ;

Daisuke Tsukamoto ;

Keisuke Yasumoto ;

Tsutomu Hashidume ;

Kenya Kamimura ;

Yuji Nakai ;

Shigeki Hirano ;

Makoto Shimizu ;

Ryo Kominami ;

Ryuichiro Sato .

Scientific Reports, 6

[37] The Majority of the Serine/Threonine Phosphorylation Sites in Bcl11b Protein Are Dispensable for the Differentiation of T Cells [J].

Okuyama, Kazuki ;

Nomura, Aneela ;

Nishino, Kohei ;

Tanaka, Hirokazu ;

Harly, Christelle ;

Chihara, Risa ;

Harada, Yasuyo ;

Muroi, Sawako ;

Kubo, Masato ;

Kosako, Hidetaka ;

Taniuchi, Ichiro .

JOURNAL OF IMMUNOLOGY, 2023, 210 (11) :1728-1739

[38] Inhibition of BCL11B Expression Leads to Apoptosis of Malignant T Cells but Not CD34+ [J].

Huang, Xin ;

Chen, Si ;

Chen, Shaohua ;

Yang, Lijian ;

Shen, Qi ;

Grabarczyk, Piotr ;

Przybylski, Grzegorz K. ;

Schmidt, Christian A. ;

Li, Yangqiu .

BLOOD, 2010, 116 (21) :1539-1539

[39] The role of BCL11B in T-cell neoplasia survival and proliferation [J].

Grabarczyk, P. ;

Naehse, V ;

Delin, M. ;

Przybylski, G. ;

Depke, M. ;

Hildebrandt, P. ;

Volker, U. ;

Schmidt, C. A. .

ONKOLOGIE, 2010, 33 :254-255

[40] BCL11B Mutations In T-Cell Acute Lymphoblastic Leukemia [J].

Keersmaecker, Kim De ;

Jose Real, Pedro ;

Della Gatta, Giusy ;

Palomero, Teresa ;

Sulis, Maria Luisa ;

Tosello, Valeria ;

Van Vlierberghe, Pieter ;

Barnes, Kelly ;

Castillo, Mireia ;

Sole, Xavier ;

Hadler, Michael ;

Lenz, Jack ;

Aplan, Peter ;

Kelliher, Michelle ;

Kee, Barbara L. ;

Pandolfi, Pier Paolo ;

Kappes, Dietmar ;

Gounari, Fotini ;

Petrie, Howard ;

Van der Meulen, Joni ;

Speleman, Frank ;

Paietta, Elisabeth ;

Racevskis, Janis ;

Tallman, Martin ;

Rowe, Jacob M. ;

Soulier, Jean ;

Avran, David ;

Cave, Helene ;

Dastugue, Nicole ;

Raimondi, Susana C. ;

Meijerink, Jules ;

Cordon-Cardo, Carlos ;

Califano, Andrea ;

Ferrando, Adolfo .

BLOOD, 2010, 116 (21) :210-210

← 1 2 3 4 5 →