Switch hitter: Bcl11b in T cells and ILC2s

被引：1

作者：

Harly, Christelle ^{[1
,2
]}

Bhandoola, Avinash ^{[3
]}

机构：

[1] Univ Nantes, Univ Angers, CNRS, INSERM,CRCINA, Nantes, France

[2] LabEx IGO Immunotherapy, Graft, Oncol, Nantes, France

[3] NCI, Lab Genome Integr, Ctr Canc Res, NIH, Bethesda, MD 20892 USA

来源：

JOURNAL OF EXPERIMENTAL MEDICINE | 2020年 / 217卷 / 01期

关键词：

D O I：

10.1084/jem.20191739

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

In this issue of JEM, Hosokawa et al. (https://doi.org/10.1084/jem.20190972) establish that transcription factor Bcl11b regulates almost completely distinct sets of genes in T cell precursors and ILC2s. To understand how this occurs, they identify multiple levels of functional regulation for Bcl11b that are used differently by T cell precursors and ILC2s.

引用

页数：2

共 50 条

[1] The Regulation of Differentiation and Proliferation of the BCL11B Gene In T Cells [J].

Chen, Si ;

Chen, Shao-Hua ;

Yang, Lijian ;

Zheng, Haitao ;

Huang, Xin ;

Li, Bo ;

Grabarczyk, Piotr ;

Przybylski, Grzegorz K. ;

Schmidt, Christian A. ;

Li, Yangqiu .

BLOOD, 2010, 116 (21) :1142-1142

[2] BCL11b调控ILC2机制的研究进展 [J].

虞文坤 ;

贾海英 .

湖北民族学院学报(医学版), 2019, 36 (03) :64-66+70

[3] BCL11B knockdown leads to apoptosis of malignant T-cells [J].

Dittmann, K. ;

Grabarczyk, P. ;

Dittmann, K. ;

Przybylski, G. K. ;

Depke, M. ;

Voelker, U. ;

Bahr, J. ;

Assmus, K. ;

Broecker, B. ;

Walther, R. ;

Schmidtz, C. A. .

HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 2007, 92 :53-53

[4] The role of BCL11B in regulating the proliferation of human naive T cells [J].

Chen, Si ;

Huang, Xin ;

Chen, Shaohua ;

Yang, Lijian ;

Shen, Qi ;

Zheng, Haitao ;

Li, Bo ;

Grabarczyk, Piotr ;

Przybylski, Grzegorz K. ;

Schmidt, Christian A. ;

Li, Yangqiu .

HUMAN IMMUNOLOGY, 2012, 73 (05) :456-464

[5] BCL11B Upregulates the Expression of RelA in T Cells Stimulated with Staphylococcal Enterotoxin A [J].

Yan, Y. ;

Wang, S. ;

Lin, C. .

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 2022, 174 (02) :259-264

[6] BCL11B Upregulates the Expression of RelA in T Cells Stimulated with Staphylococcal Enterotoxin A [J].

Y. Yan ;

S. Wang ;

C. Lin .

Bulletin of Experimental Biology and Medicine, 2022, 174 :259-264

[7] Bcl11b is required for differentiation and survival of αβ T lymphocytes [J].

Wakabayashi, Y ;

Watanabe, H ;

Inoue, J ;

Takeda, N ;

Sakata, J ;

Mishima, Y ;

Hitomi, J ;

Yamamoto, T ;

Utsuyama, M ;

Niwa, O ;

Aizawa, S ;

Kominami, R .

NATURE IMMUNOLOGY, 2003, 4 (06) :533-539

[8] Bcl11b is required for differentiation and survival of αβ T lymphocytes [J].

Yuichi Wakabayashi ;

Hisami Watanabe ;

Jun Inoue ;

Naoki Takeda ;

Jun Sakata ;

Yukio Mishima ;

Jiro Hitomi ;

Takashi Yamamoto ;

Masanori Utsuyama ;

Ohtsura Niwa ;

Shinichi Aizawa ;

Ryo Kominami .

Nature Immunology, 2003, 4 :533-539

[9] Neuroregulation of ILC2s [J].

Dempsey, Laurie A. .

NATURE IMMUNOLOGY, 2018, 19 (04) :316-316

[10] Neuroregulation of ILC2s [J].

Laurie A. Dempsey .

Nature Immunology, 2018, 19 :316-316

← 1 2 3 4 5 →