Experimental and clinical validation of plasmadynamic therapy of wounds with nitric oxide

被引:48
作者
Shekhter, AB
Kabisov, RK
Pekshev, AV
Kozlov, NP
Perov, YL
机构
[1] Minist Hlth, PA Herzen Moscow Oncol Inst, Moscow, Russia
[2] IM Sechenov Med Acad, Moscow, Russia
[3] NE Baumann Moscow State Technol Univ, Moscow, Russia
[4] Adm President Russia, Moscow, Russia
关键词
nitric oxide; wound healing; microcirculation; inflammation; aerial plasma;
D O I
10.1007/BF02446923
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Pronounced wound-healing effect of exogenous nitric oxide obtained by the plasma chemical method was confirmed in rats with aseptic and infected wounds and in patients with complicated stubborn wounds, postradiation and trophic ulcers, necroses of transplanted skin flaps, etc. Morphological study revealed normalization of microcirculation, decreased inflammation, enhanced phagocytosis, activation of macrophages, and accelerated proliferation of fibroblasts.
引用
收藏
页码:829 / 834
页数:6
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