Building the posterior lateral line system in zebrafish

被引:88
作者
Chitnis, Ajay B. [1 ]
Nogare, Damian Dalle [1 ]
Matsuda, Miho [1 ]
机构
[1] Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Program Genom Dev, NIH, Bethesda, MD USA
关键词
lateral line; zebrafish; pattern formation; self-organization; neuromasts; COLLECTIVE CELL-MIGRATION; CHEMOKINE RECEPTOR CXCR4; HAIR-CELLS; POSTEMBRYONIC DEVELOPMENT; WNT/BETA-CATENIN; TISSUE MIGRATION; BETA-ARRESTIN; MORPHOGENESIS; EXPRESSION; LIGAND;
D O I
10.1002/dneu.20962
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
The posterior lateral line (pLL) in zebrafish has emerged as an excellent system to study how a sensory organ system develops. Here we review recent studies that illustrate how interactions between multiple signaling pathways coordinate cell fate, morphogenesis, and collective migration of cells in the posterior lateral line primordium. These studies also illustrate how the pLL system is contributing much more broadly to our understanding of mechanisms operating during the growth, regeneration, and self-organization of other organ systems during development and disease. (c) 2011 Wiley Periodicals, Inc. Develop Neurobiol 72: 234255, 2012
引用
收藏
页码:234 / 255
页数:22
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