Cervical Precancers and Cancers Attributed to HPV Types by Race and Ethnicity: Implications for Vaccination, Screening, and Management

被引:18
作者
Mix, Jacqueline [1 ]
Saraiya, Mona [1 ]
Hallowell, Benjamin D. [1 ]
Befano, Brian [2 ]
Cheung, Li C. [3 ]
Unger, Elizabeth R. [4 ]
Gargano, Julia W. [5 ]
Markowitz, Lauri E. [5 ]
Castle, Philip E. [3 ,6 ]
Raine-Bennett, Tina [7 ]
Walker, Joan [8 ]
Zuna, Rosemary [8 ]
Schiffman, Mark [3 ]
Wentzensen, Nicolas [3 ]
Gage, Julia C. [3 ]
机构
[1] Ctr Dis Control & Prevent, Div Canc Prevent & Control, Atlanta, GA 30341 USA
[2] Informat Management Serv Inc, Calverton, MD USA
[3] NCI, Div Canc Epidemiol & Genet, Rockville, MD USA
[4] Ctr Dis Control & Prevent, Div High Consequence Pathogens & Pathol, Atlanta, GA 30341 USA
[5] Ctr Dis Control & Prevent, Div Viral Dis, Atlanta, GA 30341 USA
[6] NCI, Div Canc Prevent, Rockville, MD USA
[7] Kaiser Permanente Northern Calif, Div Res, Oakland, CA USA
[8] Univ Oklahoma, Hlth Sci Ctr, Oklahoma City, OK USA
来源
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE | 2022年 / 114卷 / 06期
基金
美国国家卫生研究院;
关键词
HUMAN-PAPILLOMAVIRUS TYPES; ADVISORY-COMMITTEE; RECOMMENDATIONS; PREVALENCE;
D O I
10.1093/jnci/djac034
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Background Racial and ethnic variations in attribution of cervical precancer and cancer to human papillomavirus (HPV) types may result in different HPV vaccine protection, screening test coverage, and clinical management. Methods Pooling data from 7 US studies, we calculated the proportional attribution of precancers and cancers to HPV types using HPV DNA typing from diagnosis. All statistical tests were 2-sided. Results For all racial and ethnic groups, most cases of cervical intraepithelial neoplasia grade 3 (CIN3) (84.2%-90.8% of 5526) and squamous cell carcinoma (SCC) (90.4%-93.8% of 1138) were attributed to types targeted by the 9-valent vaccine. A higher proportion of CIN3s were attributed to nonvaccine HPV types among non-Hispanic Black women (15.8%) compared with non-Hispanic Asian or Pacific Islander (9.7%; P = .002), non-Hispanic White (9.2%; P < .001), and Hispanic (11.3%; P = .004) women. The proportion of SCCs attributed to 9-valent types was similar by race and ethnicity (P = .80). A higher proportion of CIN3s were attributed to nonvaccine HPV35 among non-Hispanic Black (9.0%) compared with non-Hispanic Asian or Pacific Islander (2.2%), non-Hispanic White (2.5%), and Hispanic (3.0%; all P < .001) women. Compared with CIN3, the proportion of SCCs attributed to HPV35 among non-Hispanic Black women (3.2%) was lower and closer to other groups (0.3%-2.1%; P = .70). Conclusion The 9-valent HPV vaccine will prevent nearly all cervical precancers and invasive cancers among major racial and ethnic groups in the United States. Adding HPV35 to vaccines could prevent a small percentage of CIN3s and SCCs, with greater potential impact for CIN3s among Black women. HPV screening tests target high-risk HPV types, including HPV35. Future genotyping triage strategies could consider the importance of HPV35- and other HPV16-related types.
引用
收藏
页码:845 / 853
页数:9
相关论文
共 33 条
[1]   The causal relation between human papillomavirus and cervical cancer [J].
Bosch, FX ;
Lorincz, A ;
Muñoz, N ;
Meijer, CJLM ;
Shah, KV .
JOURNAL OF CLINICAL PATHOLOGY, 2002, 55 (04) :244-265
[2]  
BOUVARD V, 2009, LANCET ONCOL, V10, P321, DOI [DOI 10.1016/S1470-2045(09)70096-8, 10.1016/s1470-2045]
[3]   Screening for Colorectal Cancer: US Preventive Services Task Force Recommendation Statement [J].
Calonge, Ned ;
Petitti, Diana B. ;
DeWitt, Thomas G. ;
Dietrich, Allen J. ;
Gregory, Kimberly D. ;
Harris, Russell ;
Isham, George ;
LeFevre, Michael L. ;
Leipzig, Roseanne M. ;
Loveland-Cherry, Carol ;
Marion, Lucy N. ;
Melnyk, Bernadette ;
Moyer, Virginia A. ;
Ockene, Judith K. ;
Sawaya, George F. ;
Yawn, Barbara P. .
ANNALS OF INTERNAL MEDICINE, 2008, 149 (09) :627-+
[4]   Comparisons of HPV DNA detection by MY09/11 PCR methods [J].
Castle, PE ;
Schiffman, M ;
Gravitt, PE ;
Kendall, H ;
Fishman, S ;
Dong, H ;
Hildesheim, A ;
Herrero, R ;
Bratti, MC ;
Sherman, ME ;
Lorincz, A ;
Schussler, JE ;
Burk, RD .
JOURNAL OF MEDICAL VIROLOGY, 2002, 68 (03) :417-423
[5]   Meta-Analysis on Prevalence and Attribution of Human Papillomavirus Types 52 and 58 in Cervical Neoplasia Worldwide [J].
Chan, Paul K. S. ;
Ho, Wendy C. S. ;
Chan, Martin C. W. ;
Wong, Martin C. S. ;
Yeung, Apple C. M. ;
Chor, Josette S. Y. ;
Hui, Mamie .
PLOS ONE, 2014, 9 (09)
[6]   2019 ASCCP Risk-Based Management Consensus Guidelines: Methods for Risk Estimation, Recommended Management, and Validation [J].
Cheung, Li C. ;
Egemen, Didem ;
Chen, Xiaojian ;
Katki, Hormuzd A. ;
Demarco, Maria ;
Wiser, Amy L. ;
Perkins, Rebecca B. ;
Guido, Richard S. ;
Wentzensen, Nicolas ;
Schiffman, Mark .
JOURNAL OF LOWER GENITAL TRACT DISEASE, 2020, 24 (02) :90-101
[7]   Cervical adenocarcinoma in situ: Human papillomavirus types and incidence trends in five states, 2008-2015 [J].
Cleveland, Angela A. ;
Gargano, Julia W. ;
Park, Ina U. ;
Griffin, Marie R. ;
Niccolai, Linda M. ;
Powell, Melissa ;
Bennett, Nancy M. ;
Saadeh, Kayla ;
Pemmaraju, Manideepthi ;
Higgins, Kyle ;
Ehlers, Sara ;
Scahill, Mary ;
Jones, Michelle L. Johnson ;
Querec, Troy ;
Markowitz, Lauri E. ;
Unger, Elizabeth R. .
INTERNATIONAL JOURNAL OF CANCER, 2020, 146 (03) :810-818
[8]   Worldwide burden of cancer attributable to HPV by site, country and HPV type [J].
de Martel, Catherine ;
Plummer, Martyn ;
Vignat, Jerome ;
Franceschi, Silvia .
INTERNATIONAL JOURNAL OF CANCER, 2017, 141 (04) :664-670
[9]   Human papillomavirus genotype attribution in invasive cervical cancer: a retrospective cross-sectional worldwide study [J].
de Sanjose, Silvia ;
Quint, Wim G. V. ;
Alemany, Laia ;
Geraets, Daan T. ;
Ellen Klaustermeier, Jo ;
Lloveras, Belen ;
Tous, Sara ;
Felix, Ana ;
Eduardo Bravo, Luis ;
Shin, Hai-Rim ;
Vallejos, Carlos S. ;
Alonso de Ruiz, Patricia ;
Lima, Marcus Aurelho ;
Guimera, Nuria ;
Clavero, Omar ;
Alejo, Maria ;
Llombart-Bosch, Antonio ;
Cheng-Yang, Chou ;
Alejandro Tatti, Silvio ;
Kasamatsu, Elena ;
Iljazovic, Ermina ;
Odida, Michael ;
Prado, Rodrigo ;
Seoud, Muhieddine ;
Grce, Magdalena ;
Usubutun, Alp ;
Jain, Asha ;
Hernandez Suarez, Gustavo Adolfo ;
Estuardo Lombardi, Luis ;
Banjo, Aekunbiola ;
Menendez, Clara ;
Javier Domingo, Efren ;
Velasco, Julio ;
Nessa, Ashrafun ;
Chichareon, Saibua C. Bunnag ;
Qiao, You Lin ;
Lerma, Enrique ;
Garland, Suzanne M. ;
Sasagawa, Toshiyuki ;
Ferrera, Annabelle ;
Hammouda, Doudja ;
Mariani, Luciano ;
Pelayo, Adela ;
Steiner, Ivo ;
Oliva, Esther ;
Meijer, Chris J. L. M. ;
Al-Jassar, Waleed Fahad ;
Cruz, Eugenia ;
Wright, Thomas C. ;
Puras, Ana .
LANCET ONCOLOGY, 2010, 11 (11) :1048-1056
[10]   A study of type-specific HPV natural history and implications for contemporary cervical cancer screening programs [J].
Demarco, Maria ;
Hyun, Noorie ;
Carter-Pokras, Olivia ;
Raine-Bennett, Tina R. ;
Cheung, Li ;
Chen, Xiaojian ;
Hammer, Anne ;
Campos, Nicole ;
Kinney, Walter ;
Gage, Julia C. ;
Befano, Brian ;
Perkins, Rebecca B. ;
He, Xin ;
Dallal, Cher ;
Chen, Jie ;
Poitras, Nancy ;
Mayrand, Marie-Helene ;
Coutlee, Francois ;
Burk, Robert D. ;
Lorey, Thomas ;
Castle, Philip E. ;
Wentzensen, Nicolas ;
Schiffman, Mark .
ECLINICALMEDICINE, 2020, 22