GPU accelerated Cartesian GRAPPA reconstruction using CUDA

Background and Objective: GRAPPA (Generalized Auto-calibrating Partially Parallel Acquisition) is an advanced parallel MRI reconstruction method (pMRI) that enables under-sampled data acquisition with multiple receiver coils to reduce the MRI scan time and reconstructs artifact free image from the acquired under-sampled data. However, the reduction in MRI scan time comes at the expense of long reconstruction time. It is because the GRAPPA reconstruction time shows exponential growth with increasing number of receiver coils. Consequently, the conventional CPU platforms may not adhere to the requirements of fast data processing for MR image reconstruction.& nbsp;Methods: Graphics Processing Units (GPUs) have recently emerged as a viable commodity hardware to reduce the reconstruction time of pMRI methods. This paper presents a novel GPU based implementation of GRAPPA using custom built CUDA kernels, to meet the rising demands of fast MRI processing. The proposed framework exploits intrinsic parallelism in the calibration and synthesis phases of GRAPPA reconstruction process, aiming to achieve high speed MR image reconstruction for various GRAPPA configuration settings using different number of receiver coils, auto-calibration signals (ACS), sizes of GRAPPA kernel and acceleration factors. In-vivo experiments (using 8, 12 and 30 receiver coils) are performed to compare the performance of the proposed GPU accelerated GRAPPA with the CPU based GRAPPA extensions and GPU counterpart.& nbsp;Results: The results indicate that the proposed method achieves up to asymptotic to 47.8x, asymptotic to 17x & nbsp;and asymptotic to 3.8x & nbsp;speed up gains over multicore CPU (single thread), multicore CPU (8 thread) and Gadgetron (GPU based GRAPPA) respectively, without compromising the reconstruction accuracy.& nbsp;Conclusions: The proposed method reduces the GRAPPA reconstruction time by employing the calibration phase (GRAPPA weights estimation) and synthesis phase (interpolation) on GPU. Our study shows that the proposed GPU based parallel framework for GRAPPA reconstruction provides a solution for highspeed image reconstruction while maintaining the quality of the reconstructed images. (C)& nbsp;2022 Elsevier Inc. All rights reserved.