Evolution of Endovascular Therapy in Acute Stroke: Implications of Device Development

被引：24

作者：

Balasubramaian, Adithya ^{[1
]}

Mitchell, Peter ^{[1
]}

Dowling, Richard ^{[1
]}

Yan, Bernard ^{[1
]}

机构：

[1] Royal Melbourne Hosp, Comprehens Stroke Ctr, Parkville, Vic, Australia

来源：

JOURNAL OF STROKE | 2015年 / 17卷 / 02期

关键词：

Mechanical Thrombectomy; Acute Ishemic Stroke; Clot Retrieval; Endovascular; Stentriever; ACUTE ISCHEMIC-STROKE; TISSUE-PLASMINOGEN ACTIVATOR; RANDOMIZED-TRIAL; MECHANICAL THROMBECTOMY; PENUMBRA SYSTEM; REVASCULARIZATION; RECANALIZATION; THROMBOLYSIS; INTERVENTION; PROUROKINASE;

D O I：

10.5853/jos.2015.17.2.127

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Intravenous thrombolysis is. an effective treatment for acute ischaemic stroke. However, vascular recanalization rates remain poor especially in the setting of large artery occlusion. On the other hand, endovascular intra-arterial therapy addresses this issue with superior recanalization rates compared with intravenous thrombolysis. Although previous randomized controlled studies of intra-arterial therapy failed to demonstrate superiority, the failings may be attributed to a combination of inferior intra-arterial devices and suboptimal selection criteria. The recent results of several randomized controlled trials have demonstrated significantly improved outcomes, underpinning the advantage of newer intra-arterial devices and superior recanalization rates, leading to renewed interest in establishing intra-arterial therapy as the gold standard for acute ischaemic stroke. The aim of this review is to outline the history and development of different intra-arterial devices and future directions in research.

引用

页码：127 / 137

页数：11

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