Gastric bypass: a risk factor for neural tube defects?

被引:21
作者
Moliterno, Jennifer A. [1 ]
DiLuna, Michael L. [1 ]
Sood, Shreya [1 ]
Roberts, Kurt E. [2 ]
Duncan, Charles C. [1 ]
机构
[1] Yale Univ, Sch Med, Dept Neurosurg, New Haven, CT 06510 USA
[2] Yale Univ, Sch Med, Dept Surg, Sect Gastroenterol Surg, New Haven, CT 06510 USA
关键词
bariatric surgery; gastric bypass surgery; neural tube defect; spina bifida;
D O I
10.3171/PED/2008/1/5/406
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Gastric bypass surgery has become a safe and acceptable surgical weight loss treatment for individuals who suffer from morbid obesity. Patients who undergo this procedure are subject to vitamin deficiencies due to an iatrogenic mal-absorptive state. Folate, a vitamin known for its role in the prevention of neural tube defects (NTDs), can be part of the deficiency spectrum resulting from this procedure. The authors describe the case of a woman who was nonadherent to multivitamin treatment after undergoing gastric bypass surgery. Her lack of understanding and appreciation of the relationship between gastric bypass surgery, folate deficiency, and NTDs may have contributed to her noncompliance with daily multivitamin consumption. As a result, her potential problems with folate absorption could have contributed to her subsequently giving birth to a child with a myelomeningocele. Thus, patient awareness and counseling along with aggressive vitamin supplementation among this particular population may help prevent the occurrence of NTDs after gastric bypass surgery.
引用
收藏
页码:406 / 409
页数:4
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