FeCl3.6H2O catalyzed diastereoselective synthesis of (L)-menthyl 4-oxo-2-arylpiperidine-3-carboxylates

被引：3
作者：
Syamala, Lakshmi V. R. Babu [1 ]
Bhat, Ramakrishna G. [1 ]
机构：
[1] Indian Inst Sci Educ & Res, Dept Chem, Dr Homi Bhabha Rd, Pune 411008, Maharashtra, India
来源：
TETRAHEDRON LETTERS | 2017年 / 58卷 / 52期
关键词：
Catalysis; Cyclization; Chiral auxiliary; aza-Michael addition; Lewis acid; DIELS-ALDER REACTIONS; ASYMMETRIC-SYNTHESIS; CONCISE SYNTHESIS; ACID; PIPERIDINES; ALKALOIDS; PYRROLIDINE; SCAFFOLDS; AUXILIARY; IMINES;
D O I：
10.1016/j.tetlet.2017.11.026
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient diastereoselective synthesis of substituted piperidines is accomplished by using catalytic amount of FeCl3:6H(2)O via intramolecular aza-Michael addition of carbamate on alkylidene beta-keto (L)menthyl esters in a very short time. (C) 2017 Elsevier Ltd. All rights reserved.
引用
收藏
页码：4836 / 4840
页数：5
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