The first stereoselective total synthesis of quinine

被引：171

作者：

Stork, G ^{[1
]}

Niu, D ^{[1
]}

Fujimoto, A ^{[1
]}

Koft, ER ^{[1
]}

Balkovec, JM ^{[1
]}

Tata, JR ^{[1
]}

Dake, GR ^{[1
]}

机构：

[1] Columbia Univ, Dept Chem, New York, NY 10027 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2001年 / 123卷 / 14期

关键词：

D O I：

10.1021/ja004325r

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The first entirely stereoselective total synthesis of (-)-quinine is reported.

引用

页码：3239 / 3242

页数：4

共 42 条

[1]

Casteel D.A., 1997, BURGERS MED CHEM DRU, V5, P16

[2]

DESLONGCHAMPS P, 1983, STEREOELECTRONIC EFF, P211

[3] SYNTHESES IN CINCHONA ALKALOID SERIES [J].

GATES, M ;

SUGAVANAM, B ;

SCHREIBER, WL .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1970, 92 (01) :205-+

[4] REINVESTIGATION OF CLASSICAL SYNTHESIS OF CINCHONA ALKALOIDS .1. NEW SYNTHESIS OF HOMOMEROQUINENE AND QUINOTOXINE [J].

GRETE, G ;

LEE, HL ;

MITT, T ;

USKOKOVIC, MR .

HELVETICA CHIMICA ACTA, 1973, 56 (05) :1485-1494

[5] TOTAL SYNTHESIS OF CINCHONA ALKALOIDS .4. SYNTHESES VIA QUINUCLIDINE PRECURSORS [J].

GRETHE, G ;

LEE, HL ;

MITT, T ;

USKOKOVIC, MR .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1978, 100 (02) :589-593

[6] SYNTHESIS OF CINCHONA ALKALOIDS VIA QUINUCLIDINE PRECURSORS [J].

GRETHE, G ;

LEE, HL ;

MITT, T ;

USKOKOVI.MR .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1971, 93 (22) :5904-&

[7] TOTAL SYNTHESIS OF CINCHONA ALKALOIDS .3. SYNTHESES OF QUINUCLIDINE INTERMEDIATES [J].

GRETHE, G ;

LEE, HL ;

MITT, T ;

USKOKOVIC, MR .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1978, 100 (02) :581-588

[8]

Grethe G., 1983, CHEM HETEROCYCLIC 4, V23, P279

[9] TOTAL SYNTHESIS OF CINCHONA ALKALOIDS .2. STEREOSELECTIVE TOTAL SYNTHESES OF QUININE AND QUINIDINE [J].

GUTZWILLER, J ;

USKOKOVIC, MR .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1978, 100 (02) :576-581

[10] REINVESTIGATION OF CLASSICAL SYNTHESIS OF CINCHONA ALKALOIDS .2. SYNTHESIS OF QUININE AND ITS NATURALLY OCCURRING DIASTEREOMERS FROM QUINOTOXINE [J].

GUTZWILLER, J ;

USKOKOVIC, MR .

HELVETICA CHIMICA ACTA, 1973, 56 (05) :1494-1503

← 1 2 3 4 5 →