Enantioselective total synthesis of (+)-duocarmycin A, epi-(+)-duocarmycin A, and their unnatural enantiomers

被引：66

作者：

Boger, DL

McKie, JA

Nishi, T

Ogiku, T

机构：

[1] Department of Chemistry, Scripps Research Institute, San Diego, CA 92037

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 1996年 / 118卷 / 09期

关键词：

D O I：

10.1021/ja953777e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

[No abstract available]

引用

页码：2301 / 2302

页数：2

共 22 条

[1]

Boger D. L., 1991, CHEMTRACTS ORG CHEM, V4, P329

[2] TOTAL SYNTHESIS OF (+)-DUOCARMYCIN SA [J].

BOGER, DL ;

MACHIYA, K .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1992, 114 (25) :10056-10058

[3] DIASTEREOSELECTIVE DIECKMANN CONDENSATION SUITABLE FOR INTRODUCTION OF THE DUOCARMYCIN A C6 CENTER - DEVELOPMENT OF A DIVERGENT STRATEGY FOR THE TOTAL SYNTHESIS OF DUOCARMYCINS A AND SA [J].

BOGER, DL ;

NISHI, T .

BIOORGANIC & MEDICINAL CHEMISTRY, 1995, 3 (01) :67-77

[4] CC-1065 AND THE DUOCARMYCINS - UNRAVELING THE KEYS TO A NEW CLASS OF NATURALLY DERIVED DNA ALKYLATING-AGENTS [J].

BOGER, DL ;

JOHNSON, DS .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1995, 92 (09) :3642-3649

[5] (+)- AND ENT-(-)-DUOCARMYCIN SA AND (+)- AND ENT-(-)-N-BOC-DSA DNA ALKYLATION PROPERTIES - ALKYLATION SITE MODELS THAT ACCOMMODATE THE OFFSET AT-RICH ADENINE N3 ALKYLATION SELECTIVITY OF THE ENANTIOMERIC AGENTS [J].

BOGER, DL ;

JOHNSON, DS ;

YUN, WY .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1994, 116 (05) :1635-1656

[6] DUOCARMYCIN PYRINDAMYCIN DNA ALKYLATION PROPERTIES AND IDENTIFICATION, SYNTHESIS, AND EVALUATION OF AGENTS INCORPORATING THE PHARMACOPHORE OF THE DUOCARMYCIN PYRINDAMYCIN ALKYLATION SUBUNIT - IDENTIFICATION OF THE CC-1065-DUOCARMYCIN COMMON PHARMACOPHORE [J].

BOGER, DL ;

ISHIZAKI, T ;

ZARRINMAYEH, H ;

MUNK, SA ;

KITOS, PA ;

SUNTORNWAT, O .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1990, 112 (24) :8961-8971

[7] REGIOCONTROLLED NUCLEOPHILIC-ADDITION TO SELECTIVELY ACTIVATED PARA-QUINONE DIIMINES - ALTERNATIVE PREPARATION OF A KEY INTERMEDIATE EMPLOYED IN THE PREPARATION OF THE CC-1065 LEFT-HAND SUBUNIT [J].

BOGER, DL ;

ZARRINMAYEH, H .

JOURNAL OF ORGANIC CHEMISTRY, 1990, 55 (04) :1379-1390

[8] TOTAL SYNTHESIS AND PRELIMINARY EVALUATION OF (+)-DUOCARMYCIN AND ENT-(-)-DUOCARMYCIN SA [J].

BOGER, DL ;

MACHIYA, K ;

HERTZOG, DL ;

KITOS, PA ;

HOLMES, D .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1993, 115 (20) :9025-9036

[9] THE DUOCARMYCINS - SYNTHETIC AND MECHANISTIC STUDIES [J].

BOGER, DL .

ACCOUNTS OF CHEMICAL RESEARCH, 1995, 28 (01) :20-29

[10]

BOGER DL, 1990, J ORG CHEM, V55, P449

← 1 2 3 →