Efficient sampling windows for parameter estimation in mixed effects models

被引：9

作者：

Patan, Maciej ^{[1
]}

Bogacka, Barbara ^{[2
]}

机构：

[1] Univ Zielona Gora, Inst Control & Computat Engn, Ul Podgorna 50, PL-65246 Zielona Gora, Poland

[2] Univ London, Sch Math Sci, London E1 4NS, England

来源：

MODA 8 - ADVANCES IN MODEL-ORIENTED DESIGN AND ANALYSIS | 2007年

关键词：

mixed effects non-linear model; population experimental design; equivalence theorem;

D O I：

10.1007/978-3-7908-1952-6_19

中图分类号：

O1 [数学];

学科分类号：

0701 ; 070101 ;

摘要：

In the paper we present a method of calculating an efficient window design for parameter estimation in a non-linear mixed effects model. We define a window population design on the basis of a continuous design for such a model. The support points of the design belong to intervals whose boundaries are determined in a way which ensures that the efficiency of the design is high; also the width of the intervals is related to the dynamic system's behaviour.

引用

页码：147 / +

页数：2

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