Remotely nano-rupturable yolk/shell capsules for magnetically-triggered drug release

被引：51

作者：

Hu, Shang-Hsiu ^{[1
]}

Chen, You-Yin ^{[2
]}

Liu, Ta-Chung ^{[1
]}

Tung, Tsan-Hua ^{[1
]}

Liu, Dean-Mo ^{[1
]}

Chen, San-Yuan ^{[1
]}

机构：

[1] Natl Chiao Tung Univ, Dept Mat Sci & Engn, Hsinchu 300, Taiwan

[2] Natl Yang Ming Univ, Inst Biomed Engn, Taipei 112, Taiwan

来源：

CHEMICAL COMMUNICATIONS | 2011年 / 47卷 / 06期

关键词：

HUMAN EPITHELIAL CANCER; GOLD; NANOCAPSULES; NANOSPHERES; THERAPY;

D O I：

10.1039/c0cc03998e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Yolk/shell capsules containing a volume/hydrophobicity transformable core and an ultra-thin silica shell have been prepared. When an external magnetic field induced the temperature, the cores exhibit a significant triggering size shrinkage and the diameter decreases more than 10 times, causing solid shells destruction and physical collapse, leading to drug burst release.

引用

收藏

页码：1776 / 1778

页数：3

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