Catheter Ablation as First-Line Therapy for Atrial Fibrillation: Ready for Prime-Time?

被引：5
|
作者：
Carrizo, Aldo G. [1 ]
Morillo, Carlos A. [2 ,3 ]
机构：
[1] McMaster Univ, Hamilton Hlth Sci, Arrhythmia & Pacing Serv, 237 Barton St East David Braley CVSRI,Room 3C-120, Hamilton, ON L8L 2X2, Canada
[2] McMaster Univ, Arrhythmia Pacing Serv, Hamilton Hlth Sci, Dept Med, Hamilton, ON L8L 2X2, Canada
[3] David Braley CVSRI, Populat Hlth Res Inst, Room 3C-120, Hamilton, ON L8L 2X2, Canada
来源：
CURRENT CARDIOLOGY REPORTS | 2016年 / 18卷 / 08期
关键词：
Atrial fibrillation; Catheter ablation; Paroxysmal; Atrial remodeling; RADIOFREQUENCY ABLATION; ANTIARRHYTHMIC-DRUGS; WORLDWIDE SURVEY; COMPLICATIONS; PROGRESSION; MANAGEMENT; 1ST; ASSOCIATION; PREVALENCE; DIAGNOSIS;
D O I：
10.1007/s11886-016-0747-4
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Current guidelines include atrial fibrillation (AF) catheter ablation as part of the management strategy in patients that have failed at least one oral antiarrhythmic drug treatment course. However, growing evidence derived from both randomized and non-randomized studies demonstrate lower rates of AF recurrence and AF burden in patients with paroxysmal AF that are naive to antiarrhythmic drug treatment. Furthermore, progression from paroxysmal AF to persistent AF appears to be delayed by early catheter ablation of AF. The current review addresses the question of the best timing for ablation in patients with paroxysmal AF and provides the rationale for offering AF ablation as first-line therapy based on the most updated evidence available.
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收藏
页数：7
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