An eco-epidemiological model is proposed to interpret the impact of an infectious disease on ecosystem, where prey is infected by lethal bacteria and the consumption of infected prey contributes to the negative growth of predator population. Of course, the required time delay is incorporated into the model. The biodiversity conservation is concerned. Stability, persistence, and bifurcation are carried out. Finally, numerical simulations are performed to support the theoretical analysis. Copyright (C) 2016 JohnWiley & Sons, Ltd.