Bone Mineral Density in Boys Diagnosed with Autism Spectrum Disorder: A Case-Control Study

被引：13

作者：

Barnhill, Kelly ^{[1
]}

Ramirez, Lucas ^{[1
,3
]}

Gutierrez, Alan ^{[1
]}

Richardson, Wendy ^{[1
]}

Marti, C. Nathan ^{[2
]}

Potts, Amy ^{[1
,4
]}

Shearer, Rebeca ^{[1
]}

Schutte, Claire ^{[1
]}

Hewitson, Laura ^{[1
]}

机构：

[1] Johnson Ctr Child Hlth & Dev, 1700 Rio Grande St, Austin, TX 78701 USA

[2] Abacist Analyt LLC, Austin, TX 78711 USA

[3] XLHealth, Care Improvement Plus Practitioners, Pleasant Grove, UT USA

[4] Oklahoma City Univ, Oklahoma City, OK USA

来源：

JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS | 2017年 / 47卷 / 11期

关键词：

Bone mineral density; Autism spectrum disorder; Nutrition; Gastrointestinal symptoms; Gluten-free/casein-free diet; Vitamin D; IRRITABLE-BOWEL-SYNDROME; GASTROINTESTINAL DISORDERS; CHILDREN; THERAPY; HEALTH; DEFICIENCIES; ADOLESCENTS; SYMPTOMS; PATTERNS; COMMON;

D O I：

10.1007/s10803-017-3277-z

中图分类号：

B844 [发展心理学（人类心理学）];

学科分类号：

040202 ;

摘要：

This study compared bone mineral density (BMD) of the spine obtained by dual-energy X-ray absorptiometry (DEXA), nutritional status, biochemical markers, and gastrointestinal (GI) symptoms in 4-8 year old boys with Autism Spectrum Disorder (ASD) with a group of age-matched, healthy boys without ASD. Boys with ASD had significantly lower spine BMD compared to controls but this was not correlated with any biochemical markers, dietary intake of calcium and vitamin D, elimination diet status, or GI symptomology. Reduced BMD in 4-8 year old boys with ASD appears to involve factors other than nutrient intake and GI status, and requires further study.

引用

页码：3608 / 3619

页数：12

共 57 条

[11] Evaluation, Diagnosis, and Treatment of Gastrointestinal Disorders in Individuals With ASDs: A Consensus Report [J].

Buie, Timothy ;

Campbell, Daniel B. ;

Fuchs, George J., III ;

Furuta, Glenn T. ;

Levy, Joseph ;

Van de Water, Judy ;

Whitaker, Agnes H. ;

Atkins, Dan ;

Bauman, Margaret L. ;

Beaudet, Arthur L. ;

Carr, Edward G. ;

Gershon, Michael D. ;

Hyman, Susan L. ;

Jirapinyo, Pipop ;

Jyonouchi, Harumi ;

Kooros, Koorosh ;

Kushak, Rafail ;

Levitt, Pat ;

Levy, Susan E. ;

Lewis, Jeffery D. ;

Murray, Katherine F. ;

Natowicz, Marvin R. ;

Sabra, Aderbal ;

Wershil, Barry K. ;

Weston, Sharon C. ;

Zeltzer, Lonnie ;

Winter, Harland .

PEDIATRICS, 2010, 125 :S1-S18

[12] Recommendations for Evaluation and Treatment of Common Gastrointestinal Problems in Children With ASDs [J].

Buie, Timothy ;

Fuchs, George J., III ;

Furuta, Glenn T. ;

Kooros, Koorosh ;

Levy, Joseph ;

Lewis, Jeffery D. ;

Wershil, Barry K. ;

Winter, Harland .

PEDIATRICS, 2010, 125 :S19-S29

[13] Longitudinal Examination of the Skeletal Effects of Selective Serotonin Reuptake Inhibitors and Risperidone in Boys [J].

Calarge, Chadi A. ;

Burns, Trudy L. ;

Schlechte, Janet A. ;

Zemel, Babette S. .

JOURNAL OF CLINICAL PSYCHIATRY, 2015, 76 (05) :607-613

[14] Risk factors for low bone mineral density in children and adolescents with inflammatory bowel disease [J].

Caldas Lopes, Leticia Helena ;

Sdepanian, Vera Lucia ;

Szejnfeld, Vera Lucia ;

de Morais, Mauro Batista ;

Fagundes-Neto, Ulysses .

DIGESTIVE DISEASES AND SCIENCES, 2008, 53 (10) :2746-2753

[15]

CARTER DR, 1992, J BONE MINER RES, V7, P137

[16]

Carter MJ, 2014, THER RECREAT J, V48, P275

[17] SYMPTOMATIC VITAMIN-A AND VITAMIN-D DEFICIENCIES IN AN 8-YEAR-OLD WITH AUTISM [J].

CLARK, JH ;

RHODEN, DK ;

TURNER, DS .

JOURNAL OF PARENTERAL AND ENTERAL NUTRITION, 1993, 17 (03) :284-286

[18] Bone mass acquisition in healthy children [J].

Davies, JH ;

Evans, BAJ ;

Gregory, JW .

ARCHIVES OF DISEASE IN CHILDHOOD, 2005, 90 (04) :373-378

[19] Relevance of norm values as part of the documentation of quality of life instruments for use in upper gastrointestinal disease [J].

Dimenas, E ;

Carlsson, G ;

Glise, H ;

Israelsson, B ;

Wiklund, I .

SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 1996, 31 :8-13

[20] Bone Density in Adolescents and Young Adults with Autism Spectrum Disorders [J].

Ekhlaspour, Laya ;

Baskaran, Charumathi ;

Campoverde, Karen Joanie ;

Sokoloff, Natalia Cano ;

Neumeyer, Ann M. ;

Misra, Madhusmita .

JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS, 2016, 46 (11) :3387-3391

← 1 2 3 4 5 6 →