Getting sepsis therapy right

被引:83
作者
Hotchkiss, Richard S. [1 ]
Sherwood, Edward R. [2 ]
机构
[1] Washington Univ, Sch Med, Dept Anesthesiol Med & Surg, St Louis, MO 63130 USA
[2] Vanderbilt Univ, Sch Med, Dept Anesthesiol & Pathol Microbiol & Immunol, Nashville, TN 37212 USA
关键词
IMMUNOSUPPRESSION;
D O I
10.1126/science.aaa8334
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
引用
收藏
页码:1201 / 1202
页数:2
相关论文
共 15 条
[1]   The Search for Effective Therapy for Sepsis Back to the Drawing Board? [J].
Angus, Derek C. .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2011, 306 (23) :2614-2615
[2]   Immunosuppression in Patients Who Die of Sepsis and Multiple Organ Failure [J].
Boomer, Jonathan S. ;
To, Kathleen ;
Chang, Kathy C. ;
Takasu, Osamu ;
Osborne, Dale F. ;
Walton, Andrew H. ;
Bricker, Traci L. ;
Jarman, Stephen D., II ;
Kreisel, Daniel ;
Krupnick, Alexander S. ;
Srivastava, Anil ;
Swanson, Paul E. ;
Green, Jonathan M. ;
Hotchkiss, Richard S. .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2011, 306 (23) :2594-2605
[3]   Sepsis studies need new direction [J].
Cohen, Jonathan ;
Opal, Steven ;
Calandra, Thierry .
LANCET INFECTIOUS DISEASES, 2012, 12 (07) :503-505
[4]   Immunosuppression in sepsis: a novel understanding of the disorder and a new therapeutic approach [J].
Hotchkiss, Richard S. ;
Monneret, Guillaume ;
Payen, Didier .
LANCET INFECTIOUS DISEASES, 2013, 13 (03) :260-268
[5]   Medical progress: The pathophysiology and treatment of sepsis. [J].
Hotchkiss, RS ;
Karl, IE .
NEW ENGLAND JOURNAL OF MEDICINE, 2003, 348 (02) :138-150
[6]   Immunotherapy for the Adjunctive Treatment of Sepsis: From Immunosuppression to Immunostimulation Time for a Paradigm Change? [J].
Leentjens, Jenneke ;
Kox, Matthijs ;
van der Hoeven, Johannes G. ;
Netea, Mihai G. ;
Pickkers, Peter .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2013, 187 (12) :1287-1293
[7]   Hospital Deaths in Patients With Sepsis From 2 Independent Cohorts [J].
Liu, Vincent ;
Escobar, Gabriel J. ;
Greene, John D. ;
Soule, Jay ;
Whippy, Alan ;
Angus, Derek C. ;
Iwashyna, Theodore J. .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2014, 312 (01) :90-92
[8]   The effect of age on the development and outcome of adult sepsis [J].
Martin, GS ;
Mannino, DM ;
Moss, M .
CRITICAL CARE MEDICINE, 2006, 34 (01) :15-21
[9]   Granulocyte-Macrophage Colony-stimulating Factor to Reverse Sepsis-associated Immunosuppression A Double-Blind, Randomized, Placebo-controlled Multicenter Trial [J].
Meisel, Christian ;
Schefold, Joerg C. ;
Pschowski, Rene ;
Baumann, Tycho ;
Hetzger, Katrin ;
Gregor, Jan ;
Weber-Carstens, Steffen ;
Hasper, Dietrich ;
Keh, Didier ;
Zuckermann, Heidrun ;
Reinke, Petra ;
Volk, Hans-Dieter .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2009, 180 (07) :640-648
[10]   Comment on "Translational Applications of Flow Cytometry in Clinical Practice" [J].
Monneret, Guillaume ;
Venet, Fabienne .
JOURNAL OF IMMUNOLOGY, 2012, 189 (03) :1099-1099