Practical management problems of stable chronic obstructive pulmonary disease in the elderly

被引:18
作者
Pistelli, Riccardo [2 ]
Ferrara, Letizia [3 ]
Misuraca, Clementina [4 ]
Bustacchini, Silvia [1 ]
机构
[1] INRCA Ancona, Sci Direct, I-60124 Ancona, Italy
[2] Catholic Univ, Dept Resp Physiol, Rome, Italy
[3] INRCA Ancona, Med Direct, I-60124 Ancona, Italy
[4] Res Hosp Casatenovo, INRCA, Unit Pulm Rehabil, Casatenovo, Italy
关键词
chronic obstructive pulmonary disease; elderly; guidelines; older patients; ABANDON FEV1/FVC LESS-THAN-0.70; AIRWAY-OBSTRUCTION; OF-LIFE; NUTRITIONAL-STATUS; COPD; FAILURE; VENTILATION; ROFLUMILAST; TIOTROPIUM; SPIROMETRY;
D O I
10.1097/01.mcp.0000410747.20958.39
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Purpose of review Chronic obstructive pulmonary disease (COPD) is one of the most prevalent and increasing health problems in the elderly on a worldwide scale. The management of COPD in older patients presents practical diagnostic and treatment issues, which are reviewed with reference to the stable stage of the disease. Recent findings In the diagnostic approach of COPD in the elderly the use of spirometry is recommended, but both patient conditions (such as inability to correctly perform it due to fatigue, lack of coordination, and cognitive impairment) and metrics characteristics should be taken into account for the test performance. It has been demonstrated in population studies that the use of the fixed ratio determines a substantial overdiagnosis of COPD in the oldest patients. Other parameters have been suggested [such as the evaluation of Lower Limit of Normality (LLN) for the FEV1/FVC ratio], which may be useful to guide the diagnosis. Several nonpharmacologic - such as smoking cessation, vaccination, physical activity, and pulmonary rehabilitation, nutrition, and eventually invasive ventilation - and pharmacologic interventions have been shown to improve outcomes and have been reviewed. Effective management of COPD in older adults should always consider the ability of patients to properly use inhalers and the involvement of caregivers or family members as a useful support to care, especially when treating cognitively impaired patients. Especially in the older population, timely identification and treatment of comorbidities are also crucial, but evidence in this area is still lacking and clinical practice guidelines do not take comorbidities into account in their recommendations. Summary The Global Initiative for Obstructive Lung Disease has recommended criteria for diagnosis and management of COPD in the general population. On the contrary, available evidence suggests practical limitations in diagnostic approach and intervention strategies in older patients with stable COPD that need to be further studied for a translation into clinical practice guidelines.
引用
收藏
页码:S43 / S48
页数:6
相关论文
共 55 条
  • [31] Lifetime risk of developing chronic obstructive pulmonary disease: a longitudinal population study
    Gershon, Andrea S.
    Warner, Laura
    Cascagnette, Paul
    Victor, J. Charles
    To, Teresa
    [J]. LANCET, 2011, 378 (9795) : 991 - 996
  • [32] Chronic Obstructive Pulmonary Disease Diagnosis and Management in Older Adults
    Gooneratne, Nalaka S.
    Patel, Nirav P.
    Corcoran, Amy
    [J]. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2010, 58 (06) : 1153 - 1162
  • [33] Accuracy of N-terminal-pro-atrial natriuretic peptide in patients admitted to emergency department
    Gruson, Damien
    Rousseau, Michel F.
    Ahn, Sylvie
    Van Linden, Francoise
    Thys, Frederic
    Ketelslegers, Jean-Marie
    Verschuren, Franck
    [J]. SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION, 2008, 68 (05) : 410 - 414
  • [34] Spirometric criteria for airway obstruction -: Use percentage of FEV1/FVC ratio below the fifth percentile, not <70%
    Hansen, James E.
    Sun, Xing-Guo
    Wasserman, Karlman
    [J]. CHEST, 2007, 131 (02) : 349 - 355
  • [35] Heart Failure and Chronic Obstructive Pulmonary Disease
    Hawkins, Nathaniel M.
    Petrie, Mark C.
    MacDonald, Michael R.
    Jhund, Pardeep S.
    Fabbri, Leonardo M.
    Wikstrand, John
    McMurray, John J. V.
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2011, 57 (21) : 2127 - 2138
  • [36] Malnutrition and ageing
    Hickson, M
    [J]. POSTGRADUATE MEDICAL JOURNAL, 2006, 82 (963) : 2 - 8
  • [37] Rational Prescribing for Patients With a Reduced Life Expectancy
    Holmes, H. M.
    [J]. CLINICAL PHARMACOLOGY & THERAPEUTICS, 2009, 85 (01) : 103 - 107
  • [38] Chronic Renal Failure A Neglected Comorbidity of COPD
    Incalzi, Raffaele Antonelli
    Corsonello, Andrea
    Pedone, Claudio
    Battaglia, Salvatore
    Paglino, Giuseppe
    Bellia, Vincenzo
    [J]. CHEST, 2010, 137 (04) : 831 - 837
  • [39] Chronic obstructive pulmonary disease (COPD) and old age?
    Jarad, Nabil
    [J]. CHRONIC RESPIRATORY DISEASE, 2011, 8 (02) : 143 - 151
  • [40] Determinants of Spirometry Use and Accuracy of COPD Diagnosis in Primary Care
    Joo, Min J.
    Au, David H.
    Fitzgibbon, Marian L.
    McKell, Joanne
    Lee, Todd A.
    [J]. JOURNAL OF GENERAL INTERNAL MEDICINE, 2011, 26 (11) : 1272 - 1277