Copper-catalyzed oxidative C(sp3)-H/N-H coupling of sulfoximines and amides with simple alkanes via a radical process

被引：90

作者：

Teng, Fan ^{[1
]}

Sun, Song ^{[1
]}

Jiang, Yan ^{[1
]}

Yu, Jin-Tao ^{[1
]}

Cheng, Jiang ^{[1
]}

机构：

[1] Changzhou Univ, Jiangsu Prov Key Lab Fine Petrochem Engn, Jiangsu Key Lab Adv Catalyt Mat & Technol, Sch Petrochem Engn, Changzhou 213164, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2015年 / 51卷 / 27期

基金：

中国国家自然科学基金;

关键词：

H BOND ACTIVATION; BENZOTHIAZINE LIGAND; ALLYLIC ESTERS; ARYL IODIDES; N-ARYLATION; ARENES; NITROGEN; ACIDS; FUNCTIONALIZATION; ALKENES;

D O I：

10.1039/c5cc00839e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A copper-catalyzed oxidative C(sp(3))-H/N-H coupling of sulfoximines with simple alkanes was developed. This protocol involved C(sp(3))-N bond formation via a radical pathway and tolerated a series of functional groups, such as chloro, methyl and aryl, on the phenyl rings. Apart from sulfoximines, amides, saccharin and aniline also worked well to give the corresponding N-alkylated products.

引用

页码：5902 / 5905

页数：4

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