Proteomic Biomarkers of Heart Failure

被引:24
作者
Israr, Muhammad Zubair [1 ]
Heaney, Liam M. [1 ]
Suzuki, Toru [1 ,2 ]
机构
[1] Univ Leicester, Glenfield Hosp, NIHR Biomed Res Ctr, Dept Cardiovasc Sci, Groby Rd, Leicester LE3 9QP, Leics, England
[2] Jichi Med Univ, 3311-1 Yakushiji, Shimotsuke, Tochigi 3290498, Japan
关键词
Biomarkers; Heart failure; Prognosis; Diagnosis; Proteomics; GELATINASE-ASSOCIATED LIPOCALIN; BRAIN NATRIURETIC PEPTIDE; C-REACTIVE PROTEIN; GROWTH-DIFFERENTIATION FACTOR-15; CARDIAC TROPONIN-T; LEFT-VENTRICULAR DYSFUNCTION; PRESERVED EJECTION FRACTION; TRIMETHYLAMINE-N-OXIDE; AMINO-TERMINAL PROBNP; ACID-BINDING PROTEIN;
D O I
10.1016/j.hfc.2017.08.010
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Heart failure (HF) is associated with significant morbidity and mortality. Biomarkers are used to assist clinicians with timely diagnosis, prognosis, and risk prediction of patients for personalized treatment. Using modern proteomic methods such as mass spectrometry, an increasing number of novel biomarkers have been identified that further aid clinicians in the early diagnosis and outcome prediction of HF. This article focuses on the array of common and novel protein-based biomarkers that provide diagnostic and prognostic information in HF.
引用
收藏
页码:93 / +
页数:16
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