Localized prostate cancer

被引：119
作者：
Walsh, Patrick C.
DeWeese, Theodore L.
Eisenberger, Mario A.
机构：
[1] Johns Hopkins Med Inst, James Buchanan Brady Urol Inst, Baltimore, MD 21287 USA
[2] Johns Hopkins Med Inst, Sidney Kimmel Comprehens Canc Ctr, Baltimore, MD 21287 USA
[3] Johns Hopkins Med Inst, Dept Urol Radiat Oncol & Mol Radiat Sci, Baltimore, MD 21287 USA
[4] Johns Hopkins Med Inst, Dept Oncol, Baltimore, MD 21287 USA
来源：
NEW ENGLAND JOURNAL OF MEDICINE | 2007年 / 357卷 / 26期
关键词：
D O I：
10.1056/NEJMcp0706784
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
A 68-year-old man presents with newly diagnosed prostate cancer. Over the past 3 years, his serum prostate- specific antigen ( PSA) level has been slowly and steadily increasing ( from 4.0 ng per milliliter to 4.3 ng per milliliter to 4.7 ng per milliliter). His digital rectal examination is normal; the prostate volume, estimated by means of ultrasonography, is 48 ml, and a needle- biopsy specimen reveals an adenocarcinoma with a Gleason score of 6 ( the sum of the numbers associated with the most common and second most common histologic patterns - in this case, 3 plus 3). The adenocarcinoma involves 10% of 1 of the 12 cores. The patient otherwise is well, is taking no medication, and has normal sexual function. How should his case be managed?
引用
收藏
页码：2696 / 2705
页数：10
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