The chemistry of acylals. Part II. Formation of nitriles by treatment of acylals with trimethylsilyl azide in the presence of a Lewis acid

被引：91

作者：

Sandberg, M ^{[1
]}

Sydnes, LK ^{[1
]}

机构：

[1] Univ Bergen, Dept Chem, N-5007 Bergen, Norway

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 35期

关键词：

acylals; azides; benzonitriles;

D O I：

10.1016/S0040-4039(98)01309-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

When acylals from aliphatic and aromatic aldehydes are treated with trimethylsilyl azide in the presence of titanium(IV) chloride, the latter group of compounds is converted to the corresponding nitriles in good to excellent yields. By-products were not formed. (C) 1998 Elsevier Science Ltd. All rights reserved.

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页码：6361 / 6364

页数：4

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