Imaging Synucleinopathies

被引:33
作者
Brooks, David J. [1 ,2 ,3 ]
Tambasco, Nicola [4 ,5 ]
机构
[1] Aarhus Univ, Inst Clin Med, Dept Nucl Med, Aarhus, Denmark
[2] Imperial Coll London, Dept Med, London, England
[3] Newcastle Univ, Div Neurol, Newcastle Upon Tyne, Tyne & Wear, England
[4] Azienda Osped, Dept Neurol, Perugia, Italy
[5] Univ Perugia, Perugia, Italy
关键词
Parkinson's; MRI; PET; SPECT; MSA; DLB; MULTIPLE SYSTEM ATROPHY; PROGRESSIVE SUPRANUCLEAR PALSY; POSITRON-EMISSION-TOMOGRAPHY; F-18 DOPA PET; EARLY PARKINSONS-DISEASE; MAGNETIZATION-TRANSFER; DIFFERENTIAL-DIAGNOSIS; SUBSTANTIA-NIGRA; LEWY BODIES; IN-VIVO;
D O I
10.1002/mds.26547
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
In this review the structural and functional imaging changes associated with the synucleinopathies PD, MSA, and dementias associated with Lewy bodies are reviewed. The role of imaging for supporting differential diagnosis, detecting subclinical disease, and following disease progression is discussed and its potential use for monitoring disease progression is debated. (C) 2016 International Parkinson and Movement Disorder Society
引用
收藏
页码:814 / 829
页数:16
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