Sequence-Unrestricted, Watson-Crick Recognition of Double Helical B-DNA by (R)-MiniPEG-?PNAs

被引：76
作者：
Bahal, Raman [1 ,2 ]
Sahu, Bichismita [1 ,2 ]
Rapireddy, Srinivas [1 ,2 ]
Lee, Chong-Min [1 ,2 ]
Ly, Danith H. [1 ,2 ]
机构：
[1] Carnegie Mellon Univ, Dept Chem, Pittsburgh, PA 15213 USA
[2] Carnegie Mellon Univ, CNAST, Pittsburgh, PA 15213 USA
来源：
CHEMBIOCHEM | 2012年 / 13卷 / 01期
基金：
美国国家科学基金会; 美国国家卫生研究院;
关键词：
DNA recognition; gamma-PNA; nucleic acids; strand invasion; Watson-Crick base pairing;
D O I：
10.1002/cbic.201100646
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
[No abstract available]
引用
收藏
页码：56 / 60
页数：5
相关论文
共 48 条
[1]   Engineering polydactyl zinc-finger transcription factors [J].
Beerli, RR ;
Barbas, CF .
NATURE BIOTECHNOLOGY, 2002, 20 (02) :135-141
[2]   Combined triplex/duplex invasion of double-stranded DNA by "tail-clamp" peptide nucleic acid [J].
Bentin, T ;
Larsen, HJ ;
Nielsen, PE .
BIOCHEMISTRY, 2003, 42 (47) :13987-13995
[3]   Enhanced peptide nucleic acid binding to supercoiled DNA: Possible implications for DNA ''breathing'' dynamics [J].
Bentin, T ;
Nielsen, PE .
BIOCHEMISTRY, 1996, 35 (27) :8863-8869
[4]   A Simple Cytosine to G-Clamp Nucleobase Substitution Enables Chiral γ-PNAs to Invade Mixed-Sequence Double-Helical B-form DNA [J].
Chenna, Venugopal ;
Rapireddy, Srinivas ;
Sahu, Bichismita ;
Ausin, Cristina ;
Pedroso, Enrique ;
Ly, Danith H. .
CHEMBIOCHEM, 2008, 9 (15) :2388-2391
[5]   Capturing chromosome conformation [J].
Dekker, J ;
Rippe, K ;
Dekker, M ;
Kleckner, N .
SCIENCE, 2002, 295 (5558) :1306-1311
[6]   Kinetics and mechanism of the DNA double helix invasion by pseudocomplementary peptide nucleic acids [J].
Demidov, VV ;
Protozanova, E ;
Izvolsky, KI ;
Price, C ;
Nielsen, PE ;
Frank-Kamenetskii, MD .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (09) :5953-5958
[7]   Small-molecule-based strategies for controlling gene expression [J].
Denison, C ;
Kodadek, T .
CHEMISTRY & BIOLOGY, 1998, 5 (06) :R129-R145
[8]   RECOGNITION OF GUANINE AND ADENINE IN DNA BY CYTOSINE AND THYMINE CONTAINING PEPTIDE NUCLEIC-ACIDS (PNA) [J].
EGHOLM, M ;
NIELSEN, PE ;
BUCHARDT, O ;
BERG, RH .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1992, 114 (24) :9677-9678
[9]   DNA CHEMISTRY - HOW THE DOUBLE HELIX BREATHES [J].
FRANKKAMENETSKII, M .
NATURE, 1987, 328 (6125) :17-18
[10]   HIGHLY SELECTIVE CHEMICAL MODIFICATION OF CRUCIFORM LOOPS BY DIETHYL PYROCARBONATE [J].
FURLONG, JC ;
LILLEY, DMJ .
NUCLEIC ACIDS RESEARCH, 1986, 14 (10) :3995-4007
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