Optimization of the split-spectrum amplitude-decorrelation angiography algorithm on a spectral optical coherence tomography system

被引：94

作者：

Gao, Simon S. ^{[1
]}

Liu, Gangjun ^{[1
]}

Huang, David ^{[1
]}

Jia, Yali ^{[1
]}

机构：

[1] Casey Eye Inst, Portland, OR 97239 USA

来源：

OPTICS LETTERS | 2015年 / 40卷 / 10期

关键词：

IN-VIVO; VASCULAR PERFUSION; DOPPLER TOMOGRAPHY; MICRO-ANGIOGRAPHY; HIGH-SPEED; MICROVASCULATURE; VOLUMES;

D O I：

10.1364/OL.40.002305

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

The split-spectrum amplitude-decorrelation angiography algorithm was optimized on a spectral optical coherence tomography system using a flow phantom. The number of times the spectrum was split and the bandwidth of each split were adjusted to maximize the flow phantom decorrelation signal-to-noise ratio. The improvement in flow detection was then demonstrated with en face retinal angiograms. The optimized algorithm increased the detectable retinal microvascular flow and decreased the variability of the quantified vessel density in OCT retinal angiograms of healthy human subjects. (C) 2015 Optical Society of America

引用

页码：2305 / 2308

页数：4

共 13 条

[1] In vivo volumetric imaging of vascular perfusion within human retina and choroids with optical micro-angiography
An, Lin
Wang, Ruikang K.
[J]. OPTICS EXPRESS, 2008, 16 (15) : 11438 - 11452
[2] High speed, wide velocity dynamic range Doppler optical coherence tomography (Part IV): split spectrum processing in rotary catheter probes
Barry Vuong
Lee, Anthony M. D.
Luk, Timothy W. H.
Sun, Cuiru
Lam, Stephen
Lane, Pierre
Yang, Victor X. D.
[J]. OPTICS EXPRESS, 2014, 22 (07): : 7399 - 7415
[3] In vivo bidirectional color Doppler flow imaging of picoliter blood volumes using optical coherence tomograghy
Izatt, JA
Kulkami, MD
Yazdanfar, S
Barton, JK
Welch, AJ
[J]. OPTICS LETTERS, 1997, 22 (18) : 1439 - 1441
[4] Quantitative OCT angiography of optic nerve head blood flow
Jia, Yali
Morrison, John C.
Tokayer, Jason
Tan, Ou
Lombardi, Lorinna
Baumann, Bernhard
Lu, Chen D.
Choi, WooJhon
Fujimoto, James G.
Huang, David
[J]. BIOMEDICAL OPTICS EXPRESS, 2012, 3 (12): : 3127 - 3137
[5] Quantitative Optical Coherence Tomography Angiography of Choroidal Neovascularization in Age-Related Macular Degeneration
Jia, Yali
Bailey, Steven T.
Wilson, David J.
Tan, Ou
Klein, Michael L.
Flaxel, Christina J.
Potsaid, Benjamin
Liu, Jonathan J.
Lu, Chen D.
Kraus, Martin F.
Fujimoto, James G.
Huang, David
[J]. OPHTHALMOLOGY, 2014, 121 (07) : 1435 - 1444
[6] Split-spectrum amplitude-decorrelation angiography with optical coherence tomography
Jia, Yali
Tan, Ou
Tokayer, Jason
Potsaid, Benjamin
Wang, Yimin
Liu, Jonathan J.
Kraus, Martin F.
Subhash, Hrebesh
Fujimoto, James G.
Hornegger, Joachim
Huang, David
[J]. OPTICS EXPRESS, 2012, 20 (04): : 4710 - 4725
[7] Motion correction in optical coherence tomography volumes on a per A-scan basis using orthogonal scan patterns
Kraus, Martin F.
Potsaid, Benjamin
Mayer, Markus A.
Bock, Ruediger
Baumann, Bernhard
Liu, Jonathan J.
Hornegger, Joachim
Fujimoto, James G.
[J]. BIOMEDICAL OPTICS EXPRESS, 2012, 3 (06): : 1182 - 1199
[8] Speckle variance detection of microvasculature using swept-source optical coherence tomography
Mariampillai, Adrian
Standish, Beau A.
Moriyama, Eduardo H.
Khurana, Mamta
Munce, Nigel R.
Leung, Michael K. K.
Jiang, James
Cable, Alex
Wilson, Brian C.
Vitkin, I. Alex
Yang, Victor X. D.
[J]. OPTICS LETTERS, 2008, 33 (13) : 1530 - 1532
[9] Optimized speckle variance OCT imaging of microvasculature
Mariampillai, Adrian
Leung, Michael K. K.
Jarvi, Mark
Standish, Beau A.
Lee, Kenneth
Wilson, Brian C.
Vitkin, Alex
Yang, Victor X. D.
[J]. OPTICS LETTERS, 2010, 35 (08) : 1257 - 1259
[10] Mapping of macular substructures with optical coherence tomography for glaucoma diagnosis
Tan, Ou
Li, Gisele
Lu, Ake Tzu-Hui
Varma, Rohit
Huang, David
[J]. OPHTHALMOLOGY, 2008, 115 (06) : 949 - 956

← 1 2 →