Optimization of the split-spectrum amplitude-decorrelation angiography algorithm on a spectral optical coherence tomography system

被引：96
作者：
Gao, Simon S. [1 ]
Liu, Gangjun [1 ]
Huang, David [1 ]
Jia, Yali [1 ]
机构：
[1] Casey Eye Inst, Portland, OR 97239 USA
来源：
OPTICS LETTERS | 2015年 / 40卷 / 10期
关键词：
IN-VIVO; VASCULAR PERFUSION; DOPPLER TOMOGRAPHY; MICRO-ANGIOGRAPHY; HIGH-SPEED; MICROVASCULATURE; VOLUMES;
D O I：
10.1364/OL.40.002305
中图分类号：
O43 [光学];
学科分类号：
070207 ; 0803 ;
摘要：
The split-spectrum amplitude-decorrelation angiography algorithm was optimized on a spectral optical coherence tomography system using a flow phantom. The number of times the spectrum was split and the bandwidth of each split were adjusted to maximize the flow phantom decorrelation signal-to-noise ratio. The improvement in flow detection was then demonstrated with en face retinal angiograms. The optimized algorithm increased the detectable retinal microvascular flow and decreased the variability of the quantified vessel density in OCT retinal angiograms of healthy human subjects. (C) 2015 Optical Society of America
引用
收藏
页码：2305 / 2308
页数：4
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