Dmrt genes in the development and evolution of sexual dimorphism

被引：246

作者：

Kopp, Artyom ^{[1
]}

机构：

[1] Univ Calif Davis, Dept Ecol & Evolut, Davis, CA 95616 USA

来源：

TRENDS IN GENETICS | 2012年 / 28卷 / 04期

基金：

美国国家卫生研究院;

关键词：

DROSOPHILA-MELANOGASTER; DOUBLESEX GENE; DOMAIN GENE; TRANSCRIPTIONAL REGULATION; DNA-BINDING; C-ELEGANS; GONADAL DIFFERENTIATION; TESTIS DIFFERENTIATION; COURTSHIP BEHAVIOR; MAMMALIAN TESTIS;

D O I：

10.1016/j.tig.2012.02.002

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Most animals are sexually dimorphic, but different taxa have different sex-specific traits. Despite major differences in the genetic control of sexual development among animal lineages, the doublesex/mab-3 related (Dmrt) family of transcription factors has been shown to be involved in sex-specific differentiation in all animals that have been studied. In recent years the functions of Dmrt genes have been characterized in many animal groups, opening the way to a broad comparative perspective. This review focuses on the similarities and differences in the functions of Dmrt genes across the animal kingdom. I highlight a number of common themes in the sexual development of different taxa, discuss how Dmrt genes have acquired new roles during animal evolution, and show how they have contributed to the origin of novel sex-specific traits.

引用

页码：175 / 184

页数：10

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