Chronic myeloid leukemia CD34+cells have elevated levels of phosphatidylinositol 3,4,5 trisphosphate (PtdIns(3,4,5) P3 and lack a PtdIns(3,4,5)P3 response to cytokines and chemotactic factors;: effects reversed by imatinib

被引:5
|
作者
Hamzah, HG
Pierce, A
Stewart, WA
Downes, CP
Gray, A
Irvine, A
Spooncer, E
Whetton, AD
机构
[1] Univ Manchester, Fac Med, Christie Hosp, Manchester M20 9BX, Lancs, England
[2] Manchester Royal Infirm, Dept Clin Hematol, Manchester M13 9WL, Lancs, England
[3] Univ Dundee, Sch Life Sci, Dundee, Scotland
[4] Belfast City Hosp, Dept Hematol, Belfast BT9 7AD, Antrim, North Ireland
关键词
D O I
10.1038/sj.leu.2403919
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:1851 / 1853
页数:4
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