Sensitive Differential Pulse Stripping Voltammetry of Caffeine in Medicines and Cola Using a Sensor Based on Multi-Walled Carbon Nanotubes and Nafion

被引：0

作者：

Zhang, J. ^{[1
]}

Wang, L. P. ^{[1
]}

Guo, W. ^{[3
]}

Peng, X. D. ^{[1
]}

Li, M. ^{[1
]}

Yuan, Z. B. ^{[2
]}

机构：

[1] Inner Mongolia Univ, Sch Chem & Chem Engn, Hohhot 010021, Peoples R China

[2] Chinese Acad Sci, Grad Univ, Coll Chem & Chem Engn, Beijing 100049, Peoples R China

[3] Inner Mongolia Univ, Coll Environm & Resource Sci, Hohhot 010021, Peoples R China

来源：

INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE | 2011年 / 6卷 / 04期

基金：

中国国家自然科学基金;

关键词：

Differential pulse stripping voltammetry; sensor; carbon nanotube; nafion; caffeine; PERFORMANCE LIQUID-CHROMATOGRAPHY; CHEMICALLY-MODIFIED ELECTRODE; DOPED DIAMOND ELECTRODE; ASCORBIC-ACID; ELECTROCATALYTIC OXIDATION; DRUG FORMULATIONS; PARACETAMOL; FILM; POLYVINYLPOLYPYRROLIDONE; SPECTROPHOTOMETRY;

D O I：

暂无

中图分类号：

O646 [电化学、电解、磁化学];

学科分类号：

081704 ;

摘要：

A sensitive electrochemical sensor for the determination of caffeine (3,7 - dihydro - 1, 3, 7 - trimethyl - 1H - purine - 2, 6 - dione) based on a multi-walled carbon nanotube and a Nafion-modified glassy carbon electrode (MWCNT-Nafion/GCE) using differential pulse adsorptive stripping voltammetry is presented. The surface micromorphology of the MWCNT-Nafion/GCE as well as the effects of pH, scan rate, accumulation potential and time were investigated by scanning electron microscopy, atomic force microscopy and other electrochemical techniques. At optimal test conditions, the calibration curves for the determination of caffeine showed two linear responses. The first linear range was from 2.945 to 377.0 mu M, with a detection limit of 0.513 mu M (based on 3 sigma), and the second linear range was from 377.0 to 2356 mu M. The sensor was then successfully utilised for the determination of caffeine in real samples of "Sanlietong" tablets and Cola.

引用

页码：997 / 1006

页数：10

共 32 条

[1] Determination of caffeine at a Nafion-covered glassy carbon electrode [J].

Brunetti, Barbara ;

Desimoni, Elio ;

Casati, Paolo .

ELECTROANALYSIS, 2007, 19 (2-3) :385-388

[2]

Castro SSL, 2010, INT J ELECTROCHEM SC, V5, P1447

[3] A comparative study of the ratio spectra derivative spectrophotometry, Vierordt's method and high-performance liquid chromatography applied to the simultaneous analysis of caffeine and paracetamol in tablets [J].

Dinç, E .

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 1999, 21 (04) :723-730

[4]

Ding MZ, 2008, CHINESE J ANAL CHEM, V36, P381

[5] One-step synthesis of multiwalled carbon nanotubes-gold nanocomposites for fabricating amperometric acetylcholinesterase biosensor [J].

Du, Dan ;

Wang, Minghui ;

Cai, Jie ;

Qin, Yuehua ;

Zhang, Aidong .

SENSORS AND ACTUATORS B-CHEMICAL, 2010, 143 (02) :524-529

[6] Determination of caffeine and sympathomimetic alkaloids in weight loss supplements by high-performance liquid chromatography [J].

Evans, Ronald L. ;

Siitonen, Paul H. .

JOURNAL OF CHROMATOGRAPHIC SCIENCE, 2008, 46 (01) :61-67

[7] HPLC assay of acetylsalicylic acid, paracetamol, caffeine and phenobarbital in tablets [J].

Franeta, JT ;

Agbaba, D ;

Eric, S ;

Pavkov, S ;

Aleksic, M ;

Vladimirov, S .

FARMACO, 2002, 57 (09) :709-713

[8]

Guo GP, 2009, INT J ELECTROCHEM SC, V4, P1365

[9] Conductive diamond thin-films in electrochemistry [J].

Hupert, M ;

Muck, A ;

Wang, R ;

Stotter, J ;

Cvackova, Z ;

Haymond, S ;

Show, Y ;

Swain, GM .

[10] Sensitive adsorptive stripping voltammetric determination of paracetamol at multiwalled carbon nanotube modified basal plane pyrolytic graphite electrode [J].

Kachoosangi, Roohollah Torabi ;

Wildgoose, Gregory G. ;

Compton, Richard G. .

ANALYTICA CHIMICA ACTA, 2008, 618 (01) :54-60

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