Role of the PD-1 and PD-L1 axis in COVID-19

被引：12

作者：

Bonam, Srinivasa R. ^{[1
]}

Hu, Haitao ^{[1
,2
]}

Bayry, Jagadeesh ^{[3
]}

机构：

[1] Univ Texas Med Branch, Dept Microbiol & Immunol, Galveston, TX 77555 USA

[2] Univ Texas Med Branch, Inst Human Infect & Immun, Sealy Inst Vaccine Sci, Galveston, TX 77555 USA

[3] Indian Inst Technol Palakkad, Dept Biol Sci & Engn, Palakkad 678623, India

来源：

FUTURE MICROBIOLOGY | 2022年 / 17卷 / 13期

关键词：

adaptive immune cells; COVID-19; immune checkpoint molecules; Innate immune cells; PD-1; PD-L1; SARS-CoV-2;

D O I：

10.2217/fmb-2022-0103

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Tweetable abstract Severe COVID-19 patients display dysregulated expression of checkpoint molecules PD-1 and its ligand PD-L1, suggesting that these checkpoint molecules could be considered as prognostic markers and therapeutic targets in severe cases of COVID-19.

引用

页码：985 / 988

页数：4

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