Syntheses and Biological Activities of 1,4-Iminoalditol Derivatives as α-L-Fucosidase Inhibitors

被引：2
作者：
Moreno-Clavijo, Elena [1 ]
Carmona, Ana T. [1 ]
Moreno-Vargas, Antonio J. [1 ]
Molina, Lidia [1 ]
Robina, Inmaculada [1 ]
机构：
[1] Univ Seville, Dept Organ Chem, Fac Chem, E-41071 Seville, Spain
来源：
CHIMIA | 2011年 / 65卷 / 1-2期
关键词：
Fucosidases; Glycosidase inhibitors; Iminosugars; Pyrrolidines; GLYCOSIDASE INHIBITORS; THERMOTOGA-MARITIMA; STRUCTURAL BASIS; GLYCOSYLATION; FUCOSE; SERIES; LEADS; ACID; PURIFICATION; MECHANISM;
D O I：
10.2533/chimia.2011.40
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A review dealing with 1,4-iminoalditol (hydroxylated pyrrolidine) derivatives as inhibitors of alpha-L-fucosidases including the different synthetic approaches for their preparation as well as their inhibitory properties is presented.
引用
收藏
页码：40 / 44
页数：5
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