BMPD, a novel C2-chiral 1,3-diketone ligand;: Synthesis and application to an asymmetric catalytic reaction

被引：40

作者：

Abiko, A ^{[1
]}

Wang, GQ ^{[1
]}

机构：

[1] Kyoto Inst Technol, Venture Lab, Sakyo Ku, Kyoto 6068585, Japan

来源：

TETRAHEDRON | 1998年 / 54卷 / 38期

关键词：

D O I：

10.1016/S0040-4020(98)00695-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of BMPD, 1,3-bis(2-methylferrocenyl)propane-1,3-dione, was achieved via the Claisen condensation of a homochiral ferrocenecarboxylate and an acetylferrocene derived from the same chiral formylferrocene. Several metal complexes were prepared to exemplify the complexation ability of BMPD. A BMPD-yttrium complex was found to act as a new catalyst for silylcyanation of aldehydes with remarkable efficiency. As little as 0.2 mol% of the complex catalyzed the reaction of benzaldehyde and cyanotrimethylsilane to afford the cyanohydrin in 95% yield with 87% ee. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：11405 / 11420

页数：16

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