INITIAL EXPERIENCE WITH VOLUMETRIC IMRT (RAPIDARC) FOR INTRACRANIAL STEREOTACTIC RADIOSURGERY

被引:88
作者
Mayo, Charles S. [1 ]
Ding, Linda [1 ]
Addesa, Anthony [1 ]
Kadsh, Sidney [1 ]
Fitzgerald, T. J. [1 ]
Moser, Richard [1 ,2 ]
机构
[1] Univ Massachusetts, Sch Med, Dept Radiat Oncol, Worcester, MA 01655 USA
[2] Univ Massachusetts, Sch Med, Dept Surg, Div Neurosurg, Worcester, MA 01655 USA
来源
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS | 2010年 / 78卷 / 05期
关键词
RapidArc; Radiosurgery; Treatment time; INTENSITY-MODULATED RADIOTHERAPY; WHOLE-BRAIN RADIOTHERAPY; TREATMENT PLANS; ARC; METASTASES; DELIVERY; THERAPY; TUMORS; CYBERKNIFE; PHOTONS;
D O I
10.1016/j.ijrobp.2009.10.005
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Purpose Initial experience with delivering frameless stereotactic radiotherapy (SRT) using volumetric intensity-modulated radiation therapy (IMRT) delivered with RapidArc is presented Methods and Materials Treatment details for 12 patients (14 targets) with a mean clinical target volume (CTV) of 12 8 +/- 4 0 cm(3) were examined Dosimetric indices for conformality, homogeneity, and dose gradient were calculated and compared with published results for other frameless, intracranial SRT techniques, including Cyber Knife, TomoTherapy, and static beam IMRT Statistics on setup and treatment times and per patient dose validations were examined Results Dose indices compared favorably with other techniques Mean conformality, gradient, and homogeneity index values were 1 10 +/- 0 11, 64 9 +/- 14 1, 1 083 +/- 0026, respectively Median treatment times were 48 +/- 1 7 min Conclusion SRT using volumetric IMRT is a viable alternative to other techniques and enables short treatment times 1 his is anticipated to have a positive impact on radiobiological effect and for facilitating wider use of SRT (C) 2010 Elsevier Inc
引用
收藏
页码:1457 / 1466
页数:10
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