Progress in the clinical classification of systemic sclerosis

被引:9
作者
Johnson, Sindhu R. [1 ,2 ,3 ]
机构
[1] Toronto Western Hosp, Dept Med, Toronto Scleroderma Program, 399 Bathurst St, Toronto, ON M5T 2S8, Canada
[2] Mt Sinai Hosp, Toronto, ON, Canada
[3] Univ Toronto, Inst Hlth Policy Management & Evaluat, Toronto, ON, Canada
基金
加拿大健康研究院;
关键词
classification criteria; scleroderma; subset; systemic sclerosis; RHEUMATOLOGY/EUROPEAN LEAGUE; RHEUMATIC-DISEASES; AMERICAN-COLLEGE; SCLERODERMA; CRITERIA; SUBSETS; DIAGNOSIS; FEATURES; SURVIVAL; MORTALITY;
D O I
10.1097/BOR.0000000000000443
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Purpose of review Systemic sclerosis (SSc) subset classification criteria are a cornerstone of SSc research. Given changes in our understanding of the disease and limitations of the current criteria in the conduct of trials, the developments of new SSc subset criteria are underway. Recent findings This article summarizes previous iterations of SSc subset criteria, highlights current thinking about the construct underlying SSc subsets in the modern era and provides an overview of the development of new SSc subset criteria. Summary Using a combination of data-driven and expert-based innovative methodologies, a large international collaborative effort is developing new SSc subset criteria. It is anticipated that this new system of classification will shift the paradigm of how we study novel therapies in SSc.
引用
收藏
页码:568 / 573
页数:6
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