Treatment of alopecia areata with squaric acid dibutylester

被引：21

作者：

Hill, Nikki D. ^{[1
]}

Bunata, Kristin ^{[2
]}

Hebert, Adelaide A. ^{[1
]}

机构：

[1] Univ Texas Houston, Hlth Sci Ctr, Dept Dermatol, Houston, TX 77030 USA

[2] Univ Texas Houston, Sch Med, Houston, TX 77030 USA

来源：

CLINICS IN DERMATOLOGY | 2015年 / 33卷 / 03期

关键词：

CLASS-I EXPRESSION; TOPICAL IMMUNOTHERAPY; DIPHENYLCYCLOPROPENONE; DINITROCHLOROBENZENE; THERAPY; SKIN;

D O I：

10.1016/j.clindermatol.2014.12.001

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Squaric acid dibutylester is a topical sensitizing agent utilized for the treatment of alopecia areata. The mechanism of action is not fully understood, but is believed to redirect the inflammatory response by invoking allergic contact dermatitis. Several studies have compared the efficacy of squaric acid dibutylester to other treatments vs placebo with favorable results. This contribution reviews the history of the topical sensitizing agent squaric acid dibutylester and discusses the mechanism of action, the use in alopecia areata, and the efficacy and safety of this therapeutic agent. (C) 2015 Elsevier Inc. All rights reserved.

引用

页码：300 / 304

页数：5

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