Cationic surfactants as antifungal agents

被引：72

作者：

Elisa Fait, M. ^{[1
,2
]}

Bakas, Laura ^{[1
]}

Garrote, Graciela L. ^{[2
,3
]}

Morcelle, Susana R. ^{[1
,2
]}

Saparrat, Mario C. N. ^{[2
,4
,5
,6
]}

机构：

[1] UNLP, Ctr Asociado CIC PBA, CIPROVE,Ctr Asociado CICPBA,Dept Ciencias Biol, Ctr Invest Prot Vegetal,Fac Ciencias Exactas, La Plata, Buenos Aires, Argentina

[2] Consejo Nacl Invest Cient & Tecn, Consejo Nacl Invest Cient & Tecn, Buenos Aires, DF, Argentina

[3] UNLP, CONICET, CIDCA, Ctr Invest & Desarrollo Criotecnol Alimentos, La Plata, Buenos Aires, Argentina

[4] UNLP, CONICET, INFIVE, Inst Fisiol Vegetal, La Plata, Buenos Aires, Argentina

[5] UNLP, Inst Bot Carlos Spegazzini, Fac Ciencias Nat & Museo, La Plata, Buenos Aires, Argentina

[6] UNLP, Fac Ciencias Agr & Forestales, Catedra Microbiol Agr, La Plata, Buenos Aires, Argentina

来源：

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY | 2019年 / 103卷 / 01期

关键词：

Cationic surfactants; Antifungal activity; Human pathogens; Antifungal mechanism; QUATERNARY AMMONIUM-COMPOUNDS; AMINO-ACID SURFACTANTS; ANTIMICROBIAL ACTIVITY; BIOLOGICAL-ACTIVITY; IN-VITRO; PHYSICOCHEMICAL PROPERTIES; BENZALKONIUM CHLORIDE; BIOFILM FORMATION; BROMIDE CTAB; ARGININE;

D O I：

10.1007/s00253-018-9467-6

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Fungiin being responsible for causing diseases in animals and humans as well as environmental contaminations in health and storage facilitiesrepresent a serious concern to health security. Surfactants are a group of chemical compounds used in a broad spectrum of applications. The recently considered potential employment of cationic surfactants as antifungal or fungistatic agents has become a prominent issue in the development of antifungal strategies, especially if such surface-active agents can be synthesized in an eco-friendly manner. In this review, we describe the antifungal effect and the reported mechanisms of action of several types of cationic surfactants and also include a discussion of the contribution of these surfactants to the inhibition of yeast-based-biofilm formation. Furthermore, the putative mechanism of arginine-based tensioactive compounds as antifungal agents and their applications are also analyzed.

引用

页码：97 / 112

页数：16

共 113 条

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