Synthesis and bioanalytical applications of nanostructures multiloaded with quantum dots

被引：32
作者：
Goryacheva, Irina Yu. [1 ]
Speranskaya, Elena S. [1 ,2 ]
Goftman, Valentina V. [1 ,2 ]
Tang, Dianping [3 ]
De Saeger, Sarah [2 ]
机构：
[1] Saratov NG Chernyshevskii State Univ, Inst Chem, Dept Gen & Inorgan Chem, Saratov 410012, Russia
[2] Univ Ghent, Fac Pharmaceut Sci, Lab Food Anal, B-9000 Ghent, Belgium
[3] Fuzhou Univ, Key Lab Anal & Detect Food Safety, Fuzhou 350108, Peoples R China
来源：
TRAC-TRENDS IN ANALYTICAL CHEMISTRY | 2015年 / 66卷
关键词：
Bioanalysis; Bioimaging; Biolabeling; Enhanced label; Immunoassay; Multifunctional particle; Nanoparticle; Nanostructure; Quantum dot; Synthesis; WALLED CARBON NANOTUBES; REVERSE MICROEMULSION METHOD; SIGNAL AMPLIFICATION; SILICA SPHERES; SIO2; BEADS; ELECTROCHEMILUMINESCENCE DETECTION; FLUORESCENT NANOPARTICLES; NANOCRYSTALS; IMMUNOASSAY; NANOCOMPOSITES;
D O I：
10.1016/j.trac.2014.11.008
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
This review focuses on selected examples of multiloaded quantum-dot (QD) nanocomposites as novel concepts and promising labels for bioimaging and analysis. As bright, excellent, 10-nm-sized labels, providing high-intensity signal, QDs can reach higher levels when multiloaded into a single biocompatible nanocontainer. QD-containing nanocomposites combine the properties of both materials (i.e., luminescent and electrochemical characteristics of the entrapped QDs and permeability, solubility, reactivity or biocompatibility of the carrier). Approaches described include multiple QD-containing nanocomposites with different carriers organic (dendrimers and layer-by-layer hollow microcapsules), inorganic (carbon nanotubes and silica nanoparticles) and of a combined nature. We also consider and discuss promising applications in bioanalysis. (C) 2014 Elsevier B.V. All rights reserved.
引用
收藏
页码：53 / 62
页数：10
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