Carbon Dot-Based Biosensors

被引:25
作者
Jiang, Wei [1 ]
Zhao, Yuan [1 ]
Zhu, Xuecheng [1 ]
Liu, Huilin [1 ]
Sun, Baoguo [1 ]
机构
[1] Beijing Technol & Business Univ, Beijing Adv Innovat Ctr Food Nutr & Human Hlth, 11 Fucheng Rd, Beijing 100048, Peoples R China
来源
ADVANCED NANOBIOMED RESEARCH | 2021年 / 1卷 / 06期
基金
中国国家自然科学基金; 国家重点研发计划;
关键词
biosensors; carbon dots; fabrications; photoluminescence mechanisms; properties; GRAPHENE QUANTUM DOTS; ASSISTED POLYOL SYNTHESIS; VISIBLE-LIGHT; HYDROTHERMAL SYNTHESIS; UP-CONVERSION; FLUORESCENT; NITROGEN; NANOPARTICLES; NANODOTS; LUMINESCENCE;
D O I
10.1002/anbr.202000042
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
0D fluorescent carbon dots (CDs), consisting of sp(2)/sp(3) carbon skeletons with functional groups, have the advantages of good chemical stability, high biocompatibility, excellent dispersibility in water, and low photobleaching, as well as low toxicity and low cost. These interesting features allow CDs to be applicable in the field of biological imaging, optoelectronic, and energy devices, especially in the application of biosensors, which are rapidly gaining attention. Herein, CD synthesis methods are summarized in detail, and the basic scientific issues of top-down and bottom-up approaches to CDs photoluminescence mechanisms are comprehensively discussed and analyzed. Then, valuable insights into the current status of CD research for biosensor applications are provided and the basic photoluminescence properties of CDs, focusing on the CD photoluminescence mechanism from the aspects of optical absorption, up-conversion glow, static and dynamic quenching, fluorescence resonance energy transfer (FRET) quenching, photoinduced electron transfer (PET) quenching, and inner filter effect (IFE) quenching, are explained. Finally, a brief outlook is given to stimulate new ideas and promote further research on the potential use of CDs in various biosensor fields.
引用
收藏
页数:19
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