Long-term follow up of pediatric Philadelphia positive acute lymphoblastic leukemia treated with the EsPhALL2004 study: high white blood cell count at diagnosis is the strongest prognostic factor

被引:21
作者
Biondi, Andrea [1 ,2 ,3 ]
Cario, Gunnar [3 ]
De Lorenzo, Paola [1 ,4 ]
Castor, Anders [5 ]
Conter, Valentino [1 ]
Leoni, Veronica [1 ]
Gandemer, Virginie [6 ]
Pieters, Rob [7 ]
Stary, Jan [8 ]
Escherich, Gabriele [9 ]
Campbell, Myriam [10 ]
Attarbaschi, Andishe [11 ]
Li, Chi-Kong [12 ]
Vora, Ajay [13 ]
Bradtke, Jutta [14 ]
Saha, Vaskar [15 ]
Valsecchi, Maria Grazia [4 ]
Schrappe, Martin [3 ]
机构
[1] Univ Milano Bicocca, San Gerardo Hosp, Fdn MBBM, Dept Pediat, Monza, Italy
[2] Univ Milano Bicocca, Fdn MBBM, Ctr Ric Tettamanti, Dept Pediat, Monza, Italy
[3] Christian Albrechts Univ Kiel, Univ Med Ctr, Kiel, Germany
[4] Univ Milano Bicocca, Sch Med & Surg, EsPhALL Trial Data Ctr, Monza, Italy
[5] Skane Univ Hosp, Dept Pediat Oncol, Lund, Sweden
[6] CHU Hop Sud, Rennes, France
[7] Princess Maxima Ctr Pediat Oncol, Utrecht, Netherlands
[8] Univ Hosp Motol, Dept Pediat Hematol & Oncol, Prague, Czech Republic
[9] Univ Med Ctr Eppendorf, Clin Pediat Hematol & Oncol, Hamburg, Germany
[10] Hosp Roberto del Rio, PINDA, Chilean Natl Pediat Oncol Grp, Santiago, Chile
[11] Med Univ Vienna, St Anna Childrens Hosp, Dept Pediat & Adolescent Med, Dept Pediat Hematol & Oncol, Vienna, Austria
[12] Chinese Univ Hong Kong, Hong Kong, Peoples R China
[13] Great Ormond St Hosp Sick Children, London, England
[14] Justus Liebig Univ, Dept Pediat Hematol & Oncol, Giessen, Germany
[15] Univ Manchester, Fac Biol Med & Hlth, Sch Med Sci, Div Canc Sci, Manchester, Lancs, England
关键词
acute lymphoblastic leukemia (ALL); Philadelphia chromosome; pre-tyrosine kinase inhibitors (TKIs); CHROMOSOME; CHILDHOOD; IMATINIB; CHILDREN; THERAPY; TRIALS;
D O I
10.3324/haematol.2018.199422
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:E13 / E16
页数:4
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