Long-term follow up of pediatric Philadelphia positive acute lymphoblastic leukemia treated with the EsPhALL2004 study: high white blood cell count at diagnosis is the strongest prognostic factor

被引：21

作者：

Biondi, Andrea ^{[1
,2
,3
]}

Cario, Gunnar ^{[3
]}

De Lorenzo, Paola ^{[1
,4
]}

Castor, Anders ^{[5
]}

Conter, Valentino ^{[1
]}

Leoni, Veronica ^{[1
]}

Gandemer, Virginie ^{[6
]}

Pieters, Rob ^{[7
]}

Stary, Jan ^{[8
]}

Escherich, Gabriele ^{[9
]}

Campbell, Myriam ^{[10
]}

Attarbaschi, Andishe ^{[11
]}

Li, Chi-Kong ^{[12
]}

Vora, Ajay ^{[13
]}

Bradtke, Jutta ^{[14
]}

Saha, Vaskar ^{[15
]}

Valsecchi, Maria Grazia ^{[4
]}

Schrappe, Martin ^{[3
]}

机构：

[1] Univ Milano Bicocca, San Gerardo Hosp, Fdn MBBM, Dept Pediat, Monza, Italy

[2] Univ Milano Bicocca, Fdn MBBM, Ctr Ric Tettamanti, Dept Pediat, Monza, Italy

[3] Christian Albrechts Univ Kiel, Univ Med Ctr, Kiel, Germany

[4] Univ Milano Bicocca, Sch Med & Surg, EsPhALL Trial Data Ctr, Monza, Italy

[5] Skane Univ Hosp, Dept Pediat Oncol, Lund, Sweden

[6] CHU Hop Sud, Rennes, France

[7] Princess Maxima Ctr Pediat Oncol, Utrecht, Netherlands

[8] Univ Hosp Motol, Dept Pediat Hematol & Oncol, Prague, Czech Republic

[9] Univ Med Ctr Eppendorf, Clin Pediat Hematol & Oncol, Hamburg, Germany

[10] Hosp Roberto del Rio, PINDA, Chilean Natl Pediat Oncol Grp, Santiago, Chile

[11] Med Univ Vienna, St Anna Childrens Hosp, Dept Pediat & Adolescent Med, Dept Pediat Hematol & Oncol, Vienna, Austria

[12] Chinese Univ Hong Kong, Hong Kong, Peoples R China

[13] Great Ormond St Hosp Sick Children, London, England

[14] Justus Liebig Univ, Dept Pediat Hematol & Oncol, Giessen, Germany

[15] Univ Manchester, Fac Biol Med & Hlth, Sch Med Sci, Div Canc Sci, Manchester, Lancs, England

来源：

HAEMATOLOGICA | 2019年 / 104卷 / 01期

关键词：

acute lymphoblastic leukemia (ALL); Philadelphia chromosome; pre-tyrosine kinase inhibitors (TKIs); CHROMOSOME; CHILDHOOD; IMATINIB; CHILDREN; THERAPY; TRIALS;

D O I：

10.3324/haematol.2018.199422

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：E13 / E16

页数：4

共 15 条

[1] Outcome of treatment in children with philadelphia chromosome-positive acute lymphoblastic leukemia [J].

Aricò, M ;

Valsecchi, MG ;

Camitta, B ;

Schrappe, M ;

Chessells, J ;

Baruchel, A ;

Gaynon, P ;

Silverman, L ;

Janka-Schaub, G ;

Kamps, W ;

Pui, CH ;

Masera, G .

NEW ENGLAND JOURNAL OF MEDICINE, 2000, 342 (14) :998-1006

[2] Clinical Outcome of Children With Newly Diagnosed Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia Treated Between 1995 and 2005 [J].

Arico, Maurizio ;

Schrappe, Martin ;

Hunger, Stephen P. ;

Carroll, William L. ;

Conter, Valentino ;

Galimberti, Stefania ;

Manabe, Atsushi ;

Saha, Vaskar ;

Baruchel, Andre ;

Vettenranta, Kim ;

Horibe, Keizo ;

Benoit, Yves ;

Pieters, Rob ;

Escherich, Gabriele ;

Silverman, Lewis B. ;

Pui, Ching-Hon ;

Valsecchi, Maria Grazia .

JOURNAL OF CLINICAL ONCOLOGY, 2010, 28 (31) :4755-4761

[3] Imatinib after induction for treatment of children and adolescents with Philadelphia-chromosome-positive acute lymphoblastic leukaemia (EsPhALL): a randomised, open-label, intergroup study [J].

Biondi, Andrea ;

Schrappe, Martin ;

De Lorenzo, Paola ;

Castor, Anders ;

Lucchini, Giovanna ;

Gandemer, Virginie ;

Pieters, Rob ;

Stary, Jan ;

Escherich, Gabriele ;

Campbell, Myriam ;

Li, Chi-Kong ;

Vora, Ajay ;

Arico, Maurizio ;

Roettgers, Silja ;

Saha, Vaskar ;

Valsecchi, Maria Grazia .

LANCET ONCOLOGY, 2012, 13 (09) :936-945

[4] Advances in therapy for Philadelphia-positive acute lymphoblastic leukaemia of childhood and adolescence [J].

Bleckmann, Kirsten ;

Schrappe, Martin .

BRITISH JOURNAL OF HAEMATOLOGY, 2016, 172 (06) :855-869

[5] Allogeneic Hematopoietic Cell Transplantation (Allogeneic HCT) for Treatment of Pediatric Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia (ALL) [J].

Burke, Michael J. ;

Cao, Qing ;

Trotz, Barb ;

Weigel, Brenda ;

Kumar, Ashish ;

Smith, Angela ;

Verneris, Michael R. .

PEDIATRIC BLOOD & CANCER, 2009, 53 (07) :1289-1294

[6] Predictive value of minimal residual disease in Philadelphia-chromosome-positive acute lymphoblastic leukemia treated with imatinib in the European intergroup study of post-induction treatment of Philadelphia-chromosome-positive acute lymphoblastic leukemia, based on immunoglobulin/T-cell receptor and BCR/ABL1 methodologies [J].

Cazzaniga, Giovanni ;

De Lorenzo, Paola ;

Alten, Julia ;

Roettgers, Silja ;

Hancock, Jeremy ;

Saha, Vaskar ;

Castor, Anders ;

Madsen, Hans O. ;

Gandemer, Virginie ;

Cave, Helene ;

Leoni, Veronica ;

Koehler, Rolf ;

Ferrari, Giulia M. ;

Bleckmann, Kirsten ;

Pieters, Rob ;

van der Velden, Vincent ;

Stary, Jan ;

Zuna, Jan ;

Escherich, Gabriele ;

zur Stadt, Udo ;

Arico, Maurizio ;

Conter, Valentino ;

Schrappe, Martin ;

Valsecchi, Maria Grazia ;

Biondi, Andrea .

HAEMATOLOGICA, 2018, 103 (01) :107-115

[7] Drug therapy - Treatment of acute lymphoblastic leukemia [J].

Pui, CH ;

Evans, WE .

NEW ENGLAND JOURNAL OF MEDICINE, 2006, 354 (02) :166-178

[8]

RIBEIRO RC, 1987, BLOOD, V70, P948

[9]

Schrappe M, 1998, BLOOD, V92, P2730

[10] Long-term results of four consecutive trials in childhood ALL performed by the ALL-BFM study group from 1981 to 1995 [J].

Schrappe, M ;

Reiter, A ;

Zimmermann, M ;

Harbott, J ;

Ludwig, WD ;

Henze, G ;

Gadner, H ;

Odenwald, E ;

Riehm, H .

LEUKEMIA, 2000, 14 (12) :2205-2222

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